Compile Data Set for Download or QSAR
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Found 20 Enz. Inhib. hit(s) with all data for entry = 611
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4441((4S,5S)-2,7-bis({[2-(1-benzofuran-2-yl)phenyl]meth...)
Affinity DataKi:  530nM ΔG°:  -36.4kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4439((4S,5S)-4,5-dihydroxy-2,7-bis({2-[2-(methylsulfany...)
Affinity DataKi:  1.10E+3nM ΔG°:  -34.6kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4427((4S,5S)-4,5-dihydroxy-2,7-bis({[2-(4-methylphenyl)...)
Affinity DataKi:  1.50E+3nM ΔG°:  -33.8kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4429((4S,5S)-2,7-bis({[2-(4-butylphenyl)phenyl]methyl})...)
Affinity DataKi:  1.90E+3nM ΔG°:  -33.2kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4423((4S,5S)-4,5-dihydroxy-2,7-bis({2-[(E)-2-phenylethe...)
Affinity DataKi:  2.00E+3nM ΔG°:  -33.1kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4432((4S,5S)-4,5-dihydroxy-2,7-bis({2-[3-(trifluorometh...)
Affinity DataKi:  2.40E+3nM ΔG°:  -32.6kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4425((4S,5S)-2,7-bis[(2-benzylphenyl)methyl]-4,5-dihydr...)
Affinity DataKi:  2.50E+3nM ΔG°:  -32.5kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4426((4S,5S)-4,5-dihydroxy-2,7-bis[(2-phenylphenyl)meth...)
Affinity DataKi:  2.50E+3nM ΔG°:  -32.5kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4428((4S,5S)-4,5-dihydroxy-2,7-bis({[2-(3-methylphenyl)...)
Affinity DataKi:  2.70E+3nM ΔG°:  -32.3kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4440((4S,5S)-4,5-dihydroxy-2,7-bis({[2-(thiophen-3-yl)p...)
Affinity DataKi:  2.70E+3nM ΔG°:  -32.3kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4424((4S,5S)-4,5-dihydroxy-2,7-bis({[2-(2-phenylethyl)p...)
Affinity DataKi:  3.00E+3nM ΔG°:  -32.1kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4430((4S,5S)-4,5-dihydroxy-2,7-bis({2-[3-(propan-2-yl)p...)
Affinity DataKi:  3.20E+3nM ΔG°:  -31.9kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4438((4S,5S)-4,5-dihydroxy-2,7-bis({[2-(2-methoxyphenyl...)
Affinity DataKi:  5.10E+3nM ΔG°:  -30.7kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4435((4S,5S)-2,7-bis({2-[4-(ethanesulfonyl)phenyl]pheny...)
Affinity DataKi:  5.20E+3nM ΔG°:  -30.7kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4434((4S,5S)-2,7-bis({[2-(4-acetylphenyl)phenyl]methyl}...)
Affinity DataKi:  5.30E+3nM ΔG°:  -30.6kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4431((4S,5S)-2,7-bis({[2-(4-fluorophenyl)phenyl]methyl}...)
Affinity DataKi:  5.30E+3nM ΔG°:  -30.6kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4436((4S,5S)-4,5-dihydroxy-2,7-bis({[2-(3-nitrophenyl)p...)
Affinity DataKi:  7.40E+3nM ΔG°:  -29.8kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4437((4S,5S)-2,7-bis({[2-(3,4-dimethoxyphenyl)phenyl]me...)
Affinity DataKi:  9.40E+3nM ΔG°:  -29.2kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4433((4S,5S)-4,5-dihydroxy-2,7-bis({[2-(4-methoxyphenyl...)
Affinity DataKi:  9.70E+3nM ΔG°:  -29.1kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Uppsala University

LigandPNGBDBM4422((4S,5S)-2,7-dibenzyl-4,5-dihydroxy-1,2,7-thiadiaze...)
Affinity DataKi: >2.00E+4nM ΔG°: >-27.3kJ/molepH: 5.0 T: 2°CAssay Description:The effects of the inhibitors on the activity of HIV-1 proteinase was determined by a fluorometric assay with an internally quenched fluorescent pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed