Compile Data Set for Download or QSAR
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Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50037429
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161330((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataIC50:  0.0900nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataIC50:  0.230nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327(CHEMBL362651 | {(R)-3-[(Biphenyl-4-sulfonyl)-isopr...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161330((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161333(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161330((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327(CHEMBL362651 | {(R)-3-[(Biphenyl-4-sulfonyl)-isopr...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161330((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161328((S)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50:  10.3nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161328((S)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327(CHEMBL362651 | {(R)-3-[(Biphenyl-4-sulfonyl)-isopr...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161333(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50:  19.6nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161330((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrilysin(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMatrilysin(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327(CHEMBL362651 | {(R)-3-[(Biphenyl-4-sulfonyl)-isopr...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161330((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50:  147nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161332((R)-4-Amino-2-[(biphenyl-4-sulfonyl)-isopropoxy-am...)
Affinity DataIC50: >300nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161332((R)-4-Amino-2-[(biphenyl-4-sulfonyl)-isopropoxy-am...)
Affinity DataIC50:  935nMAssay Description:Inhibition of human matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrilysin(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161330((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrilysin(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161330((R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-h...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327(CHEMBL362651 | {(R)-3-[(Biphenyl-4-sulfonyl)-isopr...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161332((R)-4-Amino-2-[(biphenyl-4-sulfonyl)-isopropoxy-am...)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrilysin(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327(CHEMBL362651 | {(R)-3-[(Biphenyl-4-sulfonyl)-isopr...)
Affinity DataIC50: >2.43E+4nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrilysin(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161327(CHEMBL362651 | {(R)-3-[(Biphenyl-4-sulfonyl)-isopr...)
Affinity DataIC50: >2.44E+4nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMatrilysin(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed