Compile Data Set for Download or QSAR
maximum 50k data
Found 42 Enz. Inhib. hit(s) with all data for entry = 1193
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9872((2S)-2-[(4-aminobenzene)(2-methylpropyl)sulfonamid...)
Affinity DataKi:  2.10nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9863((2S)-2-[(cyclopropylmethyl)(4-methylbenzene)sulfon...)
Affinity DataKi:  3.90nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9858((2S)-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi:  5nM ΔG°:  -48.2kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9864((2S)-2-[(cyclopentylmethyl)(4-methylbenzene)sulfon...)
Affinity DataKi:  5.20nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9871((2S)-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi:  7.20nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9862((2S)-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi:  13.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9861((2S)-2-[(2-ethylbutyl)(4-methylbenzene)sulfonamido...)
Affinity DataKi:  15.2nM ΔG°:  -45.4kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9869((2S)-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi:  17.4nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9865((2S)-2-[benzene(2-methylpropyl)sulfonamido]-6-{[(9...)
Affinity DataKi:  18.7nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9860((2S)-2-[benzyl(4-methylbenzene)sulfonamido]-6-{[(9...)
Affinity DataKi:  19.6nM ΔG°:  -44.7kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9870((2S)-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi:  42nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9868((2S)-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi:  54.9nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9877((2S)-6-[1-(9H-fluoren-9-yl)acetamido]-2-[(4-methyl...)
Affinity DataKi:  89.7nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9878((2S)-6-(9H-fluoren-9-ylformamido)-2-[(4-methylbenz...)
Affinity DataKi:  105nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9883(9H-fluoren-9-ylmethyl N-[(5S)-6-hydroxy-5-[(4-meth...)
Affinity DataKi:  105nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9884(9H-fluoren-9-ylmethyl N-[(5S)-5-carbamoyl-5-[(4-me...)
Affinity DataKi:  107nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9885(9H-fluoren-9-ylmethyl N-[(5S)-5-carbamothioyl-5-[(...)
Affinity DataKi:  127nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9873((2S)-5-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi:  180nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9887(9H-fluoren-9-ylmethyl N-[(5S)-5-(hydroxycarbamoyl)...)
Affinity DataKi:  245nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9879((2S)-6-{[(tert-butoxy)carbonyl]amino}-2-[(4-methyl...)
Affinity DataKi: >250nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9876((2S)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi: >250nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9875((2S)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi: >250nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9874((2S)-7-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi: >250nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9888(9H-fluoren-9-ylmethyl N-[(5S)-5-(hydrazinecarbonyl...)
Affinity DataKi:  254nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9867((2S)-2-[(4-tert-butylbenzene)(2-methylpropyl)sulfo...)
Affinity DataKi:  257nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9886(9H-fluoren-9-ylmethyl N-[(5S)-5-carbamimidoyl-5-[(...)
Affinity DataKi:  280nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9866((2S)-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi: >300nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9889(9H-fluoren-9-ylmethyl N-[(5S)-5-[(4-methylbenzene)...)
Affinity DataKi: >300nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9890(9H-fluoren-9-ylmethyl N-[(5S)-6-amino-5-[(4-methyl...)
Affinity DataKi: >300nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9882(9H-fluoren-9-ylmethyl N-[(5S)-5-[(4-methylbenzene)...)
Affinity DataKi: >300nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9881(Lysine derivative 43 | methyl (2S)-6-{[(9H-fluoren...)
Affinity DataKi: >300nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9859((2R)-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi:  330nM ΔG°:  -37.6kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9857((2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-6...)
Affinity DataKi:  2.00E+3nM ΔG°:  -33.1kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9856((2S)-6-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-2...)
Affinity DataKi:  8.00E+3nM ΔG°:  -29.6kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9855((2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-6...)
Affinity DataKi:  1.05E+4nM ΔG°:  -28.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9853((2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5...)
Affinity DataKi:  1.42E+4nM ΔG°:  -28.1kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9852((2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-6...)
Affinity DataKi:  1.74E+4nM ΔG°:  -27.6kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9851((2S)-6-{[(benzyloxy)carbonyl]amino}-2-{[(9H-fluore...)
Affinity DataKi:  2.15E+4nM ΔG°:  -27.1kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9854((2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5...)
Affinity DataKi:  2.62E+4nM ΔG°:  -26.6kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9850((2S)-6-{[(tert-butoxy)carbonyl]amino}-2-{[(9H-fluo...)
Affinity DataKi:  2.80E+4nM ΔG°:  -26.4kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9848((2S)-2-{[(benzyloxy)carbonyl]amino}-6-{[(tert-buto...)
Affinity DataKi: >1.00E+5nM ΔG°: >-23.2kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Pharmacor

LigandPNGBDBM9849((2S)-6-{[(tert-butoxy)carbonyl]amino}-2-[(4-methyl...)
Affinity DataKi: >1.00E+5nM ΔG°: >-23.2kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-Ser-Gln-Asn-Tyr-Pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed