Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50015928
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162519((2S,4S,5R)-2-ISOBUTYL-5-(2-THIENYL)-1-[4-(TRIFLUOR...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162527((2S,4S,5R)-2-Isobutyl-5-thiazol-2-yl-1-(4-trifluor...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162518((2S,4S,5S)-2-Isobutyl-5-isopropyl-1-(4-trifluorome...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162517((2S,4S,5R)-2-Isobutyl-5-thiophen-2-yl-1-(3-trifluo...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162531((2S,4S,5R)-1-(3,4-Dichloro-benzoyl)-2-isobutyl-5-t...)
Affinity DataIC50:  600nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162516((2S,4S,5R)-2-Isobutyl-5-pyridin-2-yl-1-(4-trifluor...)
Affinity DataIC50:  700nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162512((2S,4S,5R)-2-Isobutyl-1-(1,4,4a,8a-tetrahydro-naph...)
Affinity DataIC50:  700nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162513((2S,4S,5R)-2-(3-Methyl-butyl)-5-phenyl-1-(4-triflu...)
Affinity DataIC50:  700nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162521((2S,4S,5R)-5-Furan-2-yl-2-isobutyl-1-(4-trifluorom...)
Affinity DataIC50:  800nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162510((2S,4S,5R)-5-(4-Chloro-phenyl)-2-isobutyl-1-(4-tri...)
Affinity DataIC50:  900nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162525((2S,4S,5R)-2-Isobutyl-5-p-tolyl-1-(4-trifluorometh...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162509((2S,4S,5R)-1-(4-Chloro-benzoyl)-2-isobutyl-5-thiop...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162530((2R,4S,5R)-2-Benzyl-5-phenyl-1-(4-trifluoromethyl-...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162520((2S,4S,5R)-2-Isobutyl-1-(4-nitro-benzoyl)-5-thioph...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162524((2S,4S,5R)-2-Butyl-5-phenyl-1-(4-trifluoromethyl-b...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162529((2S,4S,5R)-2-Isobutyl-5-(2-methoxy-phenyl)-1-(4-tr...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162508((2S,4S)-1-(4-Trifluoromethyl-benzoyl)-pyrrolidine-...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162523((2S,4S,5R)-1-Benzoyl-2-isobutyl-5-thiophen-2-yl-py...)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162533((2S,4S)-1-(3,4-Dichloro-benzoyl)-pyrrolidine-2,4-d...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162511((2S,4S,5R)-2-Isobutyl-5-thiophen-2-yl-1-(4-trifluo...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162526((2S,4S,5R)-2-(3-Amino-propyl)-5-phenyl-1-(4-triflu...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162532((2S,4S,5R)-2-Methyl-5-phenyl-1-(4-trifluoromethyl-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162515((2S,4S,5R)-2-Isobutyl-1-(pyridine-4-carbonyl)-5-th...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162534((2S,4S,5R)-1-Heptanoyl-2-isobutyl-5-thiophen-2-yl-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162528((2R,4S,5R)-2-(4-Hydroxy-benzyl)-5-phenyl-1-(4-trif...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162522((2S,4S,5R)-2-Isobutyl-5-thiophen-2-yl-1-(2-trifluo...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162514((2S,4S,5R)-2-(2-Carboxy-ethyl)-5-phenyl-1-(4-trifl...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed