Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 1248
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10403BDBM10403(7-methyl-12-(morpholine-4-sulfonyl)-4-(1,3,5-trime...)
Affinity DataIC50: 4nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10392BDBM10392(7-methyl-4-(2-methylphenyl)-12-(morpholine-4-sulfo...)
Affinity DataIC50: 15nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10385BDBM10385(methyl 2-[7-methyl-12-(morpholine-4-sulfonyl)-3,5-...)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10397BDBM10397(7-methyl-3,5-dioxo-4-(1,3,5-trimethyl-1H-pyrazol-4...)
Affinity DataIC50: 16nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10399BDBM10399(2-hydroxy-N-[7-methyl-3,5-dioxo-4-(1,3,5-trimethyl...)
Affinity DataIC50: 20nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10400BDBM10400(N-(2-methoxyethyl)-7-methyl-3,5-dioxo-4-(1,3,5-tri...)
Affinity DataIC50: 21nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10401BDBM10401(methyl (2S)-2-{[7-methyl-3,5-dioxo-4-(1,3,5-trimet...)
Affinity DataIC50: 23nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10398BDBM10398(7-methyl-3,5-dioxo-4-(1,3,5-trimethyl-1H-pyrazol-4...)
Affinity DataIC50: 33nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10389BDBM10389(methyl 3-[7-methyl-12-(morpholine-4-sulfonyl)-3,5-...)
Affinity DataIC50: 37nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10381BDBM10381(4,7-dimethyl-12-(morpholine-4-sulfonyl)-4,8-diazat...)
Affinity DataIC50: 44nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10402BDBM10402(7-methyl-12-{[(2R)-2-(phenoxymethyl)pyrrolidine-1-...)
Affinity DataIC50: 55nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10395BDBM10395(7-methyl-3,5-dioxo-4-(1,3,5-trimethyl-1H-pyrazol-4...)
Affinity DataIC50: 90nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10393BDBM10393(pyrrolo[3,4-c]quinoline 6v | 7-methyl-3,5-dioxo-4-...)
Affinity DataIC50: 100nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10393BDBM10393(pyrrolo[3,4-c]quinoline 6v | 7-methyl-3,5-dioxo-4-...)
Affinity DataIC50: 140nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10378BDBM10378(7-methyl-12-(morpholine-4-sulfonyl)-4,8-diazatricy...)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10394BDBM10394(12-bromo-7-methyl-4-(1,3,5-trimethyl-1H-pyrazol-4-...)
Affinity DataIC50: 360nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10384BDBM10384(methyl 2-{12-bromo-7-methyl-3,5-dioxo-4,8-diazatri...)
Affinity DataIC50: 460nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10388BDBM10388(methyl 3-{12-bromo-7-methyl-3,5-dioxo-4,8-diazatri...)
Affinity DataIC50: 1.08E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10380BDBM10380(12-bromo-4,7-dimethyl-4,8-diazatricyclo[7.4.0.0^{2...)
Affinity DataIC50: 1.58E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10383BDBM10383(methyl 2-{12-fluoro-7-methyl-3,5-dioxo-4,8-diazatr...)
Affinity DataIC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10391BDBM10391(12-bromo-7-methyl-4-(2-methylphenyl)-4,8-diazatric...)
Affinity DataIC50: 2.54E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10382BDBM10382(methyl 2-{7-methyl-3,5-dioxo-4,8-diazatricyclo[7.4...)
Affinity DataIC50: 4.65E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10387BDBM10387(methyl 3-{12-fluoro-7-methyl-3,5-dioxo-4,8-diazatr...)
Affinity DataIC50: 5.50E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10379BDBM10379(cid_706730 | 4,7-dimethyl-4,8-diazatricyclo[7.4.0....)
Affinity DataIC50: 6.36E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10390BDBM10390(7-methyl-4-(2-methylphenyl)-4,8-diazatricyclo[7.4....)
Affinity DataIC50: 8.11E+3nMAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10386BDBM10386(methyl 3-{7-methyl-3,5-dioxo-4,8-diazatricyclo[7.4...)
Affinity DataIC50: 2.33E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10377BDBM10377(12-bromo-7-methyl-4,8-diazatricyclo[7.4.0.0^{2,6}]...)
Affinity DataIC50: 3.71E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10376BDBM10376(12-fluoro-7-methyl-4,8-diazatricyclo[7.4.0.0^{2,6}...)
Affinity DataIC50: 6.28E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed
TargetCaspase-3(Human)
Chemical Diversity Research Institute

LigandChemical structure of BindingDB Monomer ID 10375BDBM10375(7-methyl-4,8-diazatricyclo[7.4.0.0^{2,6}]trideca-1...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2006
Entry Details Article
PubMed