Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 1925
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Burnham Institute

LigandPNGBDBM15186(cid_1776570 | 4-(5-{[(5E)-2-amino-3,7-dicyano-4,6-...)
Affinity DataKi:  1.10E+3nM ΔG°:  -34.0kJ/mole IC50: 2.60E+3nMpH: 7.5 T: 2°CAssay Description:The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Burnham Institute

LigandPNGBDBM15187(3-[(2E)-3-(1H-1,3-benzodiazol-2-yl)prop-2-enoyl]-6...)
Affinity DataKi:  3.90E+3nM ΔG°:  -30.9kJ/mole IC50: 4.50E+3nMpH: 7.5 T: 2°CAssay Description:The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Burnham Institute

LigandPNGBDBM15188(5-{5-[(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)me...)
Affinity DataKi:  2.08E+4nM ΔG°:  -26.7kJ/mole IC50: 2.51E+4nMpH: 7.5 T: 2°CAssay Description:The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Burnham Institute

LigandPNGBDBM15190(3-(5-{[(5E)-2-amino-3,7-dicyano-4,6-dimethyl-5H-cy...)
Affinity DataIC50: 6.02E+4nMpH: 7.5 T: 2°CAssay Description:The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Burnham Institute

LigandPNGBDBM15189(4-(5-{[(5E)-2-amino-3,7-dicyano-4,6-dimethyl-5H-cy...)
Affinity DataIC50: 1.26E+5nMpH: 7.5 T: 2°CAssay Description:The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2007
Entry Details Article
PubMed