Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50016060
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  0.800nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)
Affinity DataKi:  1.04nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50110577(CHEMBL2314218 | 2-(2-Dimethylaminomethyl-phenylsul...)
Affinity DataKi:  1.07nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)
Affinity DataKi:  1.12nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-methyl-...)
Affinity DataKi:  1.19nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164469(N-{2-[(2-amino-4-fluorophenyl)thio]benzyl}-N,N-dim...)
Affinity DataKi:  1.46nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi:  1.83nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164473(N-(2-{[2-amino-4-(3-fluoropropyl)phenyl]thio}benzy...)
Affinity DataKi:  3.58nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164472(2-(2-Aminomethyl-phenylsulfanyl)-5-methyl-phenylam...)
Affinity DataKi:  30nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164468(2-(2-Ethylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  70.2nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164474(2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl...)
Affinity DataKi:  71.3nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164464(2-(2-Allylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  80.9nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164469(N-{2-[(2-amino-4-fluorophenyl)thio]benzyl}-N,N-dim...)
Affinity DataKi:  142nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164467(2-(2-Dimethylaminomethyl-phenylsulfanyl)-4-fluoro-...)
Affinity DataKi:  179nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-methyl-...)
Affinity DataKi:  320nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164473(N-(2-{[2-amino-4-(3-fluoropropyl)phenyl]thio}benzy...)
Affinity DataKi:  505nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164470(2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfany...)
Affinity DataKi:  518nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)
Affinity DataKi:  664nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  787nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi:  946nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50110577(CHEMBL2314218 | 2-(2-Dimethylaminomethyl-phenylsul...)
Affinity DataKi:  1.35E+3nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164468(2-(2-Ethylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  2.12E+3nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164471(5-Methyl-2-(2-propylaminomethyl-phenylsulfanyl)-ph...)
Affinity DataKi:  2.18E+3nMAssay Description:In vitro displacement of [3H]paroxetine from human serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164464(2-(2-Allylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  2.91E+3nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164471(5-Methyl-2-(2-propylaminomethyl-phenylsulfanyl)-ph...)
Affinity DataKi:  3.55E+3nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164465([3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  3.61E+3nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164464(2-(2-Allylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  3.82E+3nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164474(2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl...)
Affinity DataKi:  3.91E+3nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164470(2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfany...)
Affinity DataKi:  4.33E+3nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164474(2-{2-[(2-Fluoro-ethylamino)-methyl]-phenylsulfanyl...)
Affinity DataKi:  4.43E+3nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164472(2-(2-Aminomethyl-phenylsulfanyl)-5-methyl-phenylam...)
Affinity DataKi:  4.44E+3nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)
Affinity DataKi:  5.13E+3nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164472(2-(2-Aminomethyl-phenylsulfanyl)-5-methyl-phenylam...)
Affinity DataKi:  5.30E+3nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164467(2-(2-Dimethylaminomethyl-phenylsulfanyl)-4-fluoro-...)
Affinity DataKi:  7.04E+3nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164468(2-(2-Ethylaminomethyl-phenylsulfanyl)-5-methyl-phe...)
Affinity DataKi:  7.55E+3nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164467(2-(2-Dimethylaminomethyl-phenylsulfanyl)-4-fluoro-...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164471(5-Methyl-2-(2-propylaminomethyl-phenylsulfanyl)-ph...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]nisoxetine from human norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50091097(3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl)-b...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50110577(CHEMBL2314218 | 2-(2-Dimethylaminomethyl-phenylsul...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164470(2-{2-[(3-Fluoro-propylamino)-methyl]-phenylsulfany...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164473(N-(2-{[2-amino-4-(3-fluoropropyl)phenyl]thio}benzy...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164469(N-{2-[(2-amino-4-fluorophenyl)thio]benzyl}-N,N-dim...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-methyl-...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50119548(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-fluorom...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro displacement of [3H]GBR-12935 from human dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed