Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50037570
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164557(2-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-1H-imi...)
Affinity DataEC50:  600nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164579(1-(2,4-Dichloro-phenyl)-2-p-tolyl-1H-imidazole-4-c...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164560(2-(4-Chloro-phenyl)-1-phenyl-1H-imidazole-4-carbox...)
Affinity DataEC50:  4.20E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50125935((R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic ac...)
Affinity DataEC50:  3.50E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50055935(5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidi...)
Affinity DataEC50:  5.00E+4nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164561(1,2-Bis-(4-fluoro-phenyl)-1H-imidazole-4-carboxyli...)
Affinity DataEC50:  3.10E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164562(CHEMBL192127 | [2-(4-Chloro-phenyl)-1-(2,4-dichlor...)
Affinity DataEC50:  1.30E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164558(1,2-Bis-(4-chloro-phenyl)-1H-imidazole-4-carboxyli...)
Affinity DataEC50:  1.50E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164563(2-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-1H-imi...)
Affinity DataEC50:  4.40E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164564(2-(4-Amino-phenyl)-1-(2,4-dichloro-phenyl)-1H-imid...)
Affinity DataEC50:  4.30E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164565(1,2-Diphenyl-1H-imidazole-4-carboxylic acid ethyl ...)
Affinity DataEC50:  6.40E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164566(1-(2,4-Dichloro-phenyl)-2-phenyl-1H-imidazole-4-ca...)
Affinity DataEC50:  1.80E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164567(2-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-1H-imid...)
Affinity DataEC50:  190nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164568(2-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-1H-imi...)
Affinity DataEC50:  8.70E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164569(1-(2,4-Dichloro-phenyl)-2-(4-iodo-phenyl)-1H-imida...)
Affinity DataEC50:  450nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164571(2-(4-Acetylamino-phenyl)-1-(2,4-dichloro-phenyl)-1...)
Affinity DataEC50:  1.90E+4nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164570((3R,5S,8S,9S,10S,13S,14S,17S)-17-Acetyl-3-hydroxy-...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164572(2-(4-Methoxy-phenyl)-1-phenyl-1H-imidazole-4-carbo...)
Affinity DataEC50:  9.10E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50058046(CHEMBL526 | propofol)
Affinity DataEC50:  1.12E+4nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164573(1-(2,4-Dichloro-phenyl)-2-(4-methoxy-phenyl)-1H-im...)
Affinity DataEC50:  1.90E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164575(1-(3-Chloro-phenyl)-2-phenyl-1H-imidazole-4-carbox...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164576(2-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-1H-imid...)
Affinity DataEC50:  1.70E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164577(1-(2,4-Dichloro-phenyl)-2-(4-nitro-phenyl)-1H-imid...)
Affinity DataEC50:  2.40E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164578(2-(4-Chloro-phenyl)-1-(3,4-dichloro-phenyl)-1H-imi...)
Affinity DataEC50:  2.30E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164574(2-(4-Bromo-phenyl)-1-(2,4-dichloro-phenyl)-1H-imid...)
Affinity DataEC50:  3.40E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50164559(1-Phenyl-2-p-tolyl-1H-imidazole-4-carboxylic acid ...)
Affinity DataEC50:  4.10E+3nMAssay Description:Effective concentration against GABA-evoked chloride currents mediated by human Gamma-aminobutyric acid GABA-A receptor alpha2-beta2-gamma2L expresse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed