Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50016080
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062133(4-Methyl-piperidin-(2E)-ylideneamine | 4-Methyl-pi...)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164782((4R,4aR,5R)-4-Methyl-octahydro-quinolin-(2E)-ylide...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)
Affinity DataIC50:  31nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164784((4S,7S)-4-Methyl-octahydro-[1]pyrindin-(2E)-yliden...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062133(4-Methyl-piperidin-(2E)-ylideneamine | 4-Methyl-pi...)
Affinity DataIC50:  37nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164779((4R,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)
Affinity DataIC50:  38nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164782((4R,4aR,5R)-4-Methyl-octahydro-quinolin-(2E)-ylide...)
Affinity DataIC50:  53nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164784((4S,7S)-4-Methyl-octahydro-[1]pyrindin-(2E)-yliden...)
Affinity DataIC50:  133nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062133(4-Methyl-piperidin-(2E)-ylideneamine | 4-Methyl-pi...)
Affinity DataIC50:  146nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164781((5S,6S)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)
Affinity DataIC50:  186nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164779((4R,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164780(4-Methyl-3,4-dihydro-1H-quinolin-(2E)-ylideneamine...)
Affinity DataIC50:  240nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049255(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)
Affinity DataIC50:  240nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164781((5S,6S)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)
Affinity DataIC50:  246nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049255(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164777((4R,4aR,7aR)-4-Methyl-octahydro-[1]pyrindin-(2E)-y...)
Affinity DataIC50:  470nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164783((5S,6R)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)
Affinity DataIC50:  528nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164783((5S,6R)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)
Affinity DataIC50:  530nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164778((4S,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)
Affinity DataIC50:  610nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049255(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)
Affinity DataIC50:  630nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164782((4R,4aR,5R)-4-Methyl-octahydro-quinolin-(2E)-ylide...)
Affinity DataIC50:  830nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164776((4R,6R,9R)-4-Methyl-decahydro-cyclohepta[b]pyridin...)
Affinity DataIC50:  860nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164784((4S,7S)-4-Methyl-octahydro-[1]pyrindin-(2E)-yliden...)
Affinity DataIC50:  870nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164780(4-Methyl-3,4-dihydro-1H-quinolin-(2E)-ylideneamine...)
Affinity DataIC50:  974nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164776((4R,6R,9R)-4-Methyl-decahydro-cyclohepta[b]pyridin...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164779((4R,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164776((4R,6R,9R)-4-Methyl-decahydro-cyclohepta[b]pyridin...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062129(3,4-Dihydro-1H-quinolin-(2E)-ylideneamine | 3,4-Di...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory activity against human Neuronal nitric oxide synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164778((4S,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164778((4S,4aS,5S)-4-Methyl-octahydro-quinolin-(2E)-ylide...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164783((5S,6R)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164781((5S,6S)-[Octahydro-quinolin-(2E)-ylidene]amine | C...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062129(3,4-Dihydro-1H-quinolin-(2E)-ylideneamine | 3,4-Di...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against human Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164780(4-Methyl-3,4-dihydro-1H-quinolin-(2E)-ylideneamine...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50062129(3,4-Dihydro-1H-quinolin-(2E)-ylideneamine | 3,4-Di...)
Affinity DataIC50:  8.50E+4nMAssay Description:Inhibitory activity against human Endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed