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Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50016094
LigandPNGBDBM50164966((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  314nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50165006((S)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  23nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164968((S)-2-(3-Cyclohexyloxy-benzoyl)-1,2,3,4-tetrahydro...)
Affinity DataEC50:  20nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164967((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  292nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164969((S)-2-(3-Methoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  176nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164970((R)-2-[3-(Pyridin-2-yloxy)-benzoyl]-1,2,3,4-tetrah...)
Affinity DataEC50:  268nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164971((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  145nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164972((R)-2-(3-Benzyl-benzoyl)-1,2,3,4-tetrahydro-isoqui...)
Affinity DataEC50:  291nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164973((R)-2-[3-(4-Fluoro-phenoxy)-benzoyl]-1,2,3,4-tetra...)
Affinity DataEC50:  590nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164974((S)-2-(3,4-Dichloro-benzoyl)-1,2,3,4-tetrahydro-is...)
Affinity DataEC50:  82nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164975((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  230nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164976((S)-2-(5-Cyclohexyloxy-pyridine-3-carbonyl)-1,2,3,...)
Affinity DataEC50:  35nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164979((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  100nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164980((S)-2-(4-Cyclohexyloxy-pyridine-2-carbonyl)-1,2,3,...)
Affinity DataEC50:  9.40nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164977((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  41nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164978((R)-2-(3-Phenylsulfanyl-benzoyl)-1,2,3,4-tetrahydr...)
Affinity DataEC50:  394nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164981((S)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  119nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164983(2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinol...)
Affinity DataEC50:  294nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164985((S)-2-(3-Ethoxy-benzoyl)-1,2,3,4-tetrahydro-isoqui...)
Affinity DataEC50:  26nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164986((S)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  53nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164987((R)-2-(2-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  338nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164989((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  336nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164991((S)-2-(4-Isopropoxy-pyridine-2-carbonyl)-1,2,3,4-t...)
Affinity DataEC50:  6nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164990((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  202nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164994((S)-2-(3-Isobutoxy-benzoyl)-1,2,3,4-tetrahydro-iso...)
Affinity DataEC50:  10nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50165003((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  420nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164995((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  61nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164998((R)-2-[3-(4-Methoxy-phenoxy)-benzoyl]-1,2,3,4-tetr...)
Affinity DataEC50:  167nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164997((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  202nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50165004((S)-2-(4-Methoxy-3-phenoxy-benzoyl)-1,2,3,4-tetrah...)
Affinity DataEC50:  12nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50165001((S)-2-(4-Phenoxy-pyridine-2-carbonyl)-1,2,3,4-tetr...)
Affinity DataEC50:  20nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50165007((S)-2-(3-Chloro-benzoyl)-1,2,3,4-tetrahydro-isoqui...)
Affinity DataEC50:  51nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164982((R)-2-[3-(4-Trifluoromethyl-phenoxy)-benzoyl]-1,2,...)
Affinity DataEC50:  282nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164984((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  160nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164988((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  71nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164992((S)-2-(3-Cyclopentyloxy-benzoyl)-1,2,3,4-tetrahydr...)
Affinity DataEC50:  15nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164993((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  66nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50165000((S)-2-(3-Isopropoxy-4-methoxy-benzoyl)-1,2,3,4-tet...)
Affinity DataEC50:  3.5nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164996((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  66nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164999((S)-2-(5-Isopropoxy-pyridine-3-carbonyl)-1,2,3,4-t...)
Affinity DataEC50:  16nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50165005((S)-2-(2-Isopropoxy-pyridine-4-carbonyl)-1,2,3,4-t...)
Affinity DataEC50:  11nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50165002((S)-2-(4-Chloro-pyridine-2-carbonyl)-1,2,3,4-tetra...)
Affinity DataEC50:  79nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50164965((S)-2-(3-Isopropoxy-benzoyl)-1,2,3,4-tetrahydro-is...)
Affinity DataEC50:  6.30nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed