Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50016094
LigandChemical structure of BindingDB Monomer ID 50165000BDBM50165000((S)-2-(3-Isopropoxy-4-methoxy-benzoyl)-1,2,3,4-tet...)
Affinity DataEC50:  3.5nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164991BDBM50164991((S)-2-(4-Isopropoxy-pyridine-2-carbonyl)-1,2,3,4-t...)
Affinity DataEC50:  6nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164965BDBM50164965((S)-2-(3-Isopropoxy-benzoyl)-1,2,3,4-tetrahydro-is...)
Affinity DataEC50:  6.30nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164980BDBM50164980((S)-2-(4-Cyclohexyloxy-pyridine-2-carbonyl)-1,2,3,...)
Affinity DataEC50:  9.40nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164994BDBM50164994((S)-2-(3-Isobutoxy-benzoyl)-1,2,3,4-tetrahydro-iso...)
Affinity DataEC50:  10nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50165005BDBM50165005((S)-2-(2-Isopropoxy-pyridine-4-carbonyl)-1,2,3,4-t...)
Affinity DataEC50:  11nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50165004BDBM50165004((S)-2-(4-Methoxy-3-phenoxy-benzoyl)-1,2,3,4-tetrah...)
Affinity DataEC50:  12nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164992BDBM50164992((S)-2-(3-Cyclopentyloxy-benzoyl)-1,2,3,4-tetrahydr...)
Affinity DataEC50:  15nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164999BDBM50164999((S)-2-(5-Isopropoxy-pyridine-3-carbonyl)-1,2,3,4-t...)
Affinity DataEC50:  16nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50165001BDBM50165001((S)-2-(4-Phenoxy-pyridine-2-carbonyl)-1,2,3,4-tetr...)
Affinity DataEC50:  20nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164968BDBM50164968((S)-2-(3-Cyclohexyloxy-benzoyl)-1,2,3,4-tetrahydro...)
Affinity DataEC50:  20nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50165006BDBM50165006((S)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  23nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164985BDBM50164985((S)-2-(3-Ethoxy-benzoyl)-1,2,3,4-tetrahydro-isoqui...)
Affinity DataEC50:  26nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164976BDBM50164976((S)-2-(5-Cyclohexyloxy-pyridine-3-carbonyl)-1,2,3,...)
Affinity DataEC50:  35nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164977BDBM50164977((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  41nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50165007BDBM50165007((S)-2-(3-Chloro-benzoyl)-1,2,3,4-tetrahydro-isoqui...)
Affinity DataEC50:  51nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164986BDBM50164986((S)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  53nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164995BDBM50164995((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  61nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164993BDBM50164993((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  66nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164996BDBM50164996((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  66nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164988BDBM50164988((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  71nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50165002BDBM50165002((S)-2-(4-Chloro-pyridine-2-carbonyl)-1,2,3,4-tetra...)
Affinity DataEC50:  79nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164974BDBM50164974((S)-2-(3,4-Dichloro-benzoyl)-1,2,3,4-tetrahydro-is...)
Affinity DataEC50:  82nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164979BDBM50164979((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  100nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164981BDBM50164981((S)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  119nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164971BDBM50164971((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  145nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164984BDBM50164984((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  160nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164998BDBM50164998((R)-2-[3-(4-Methoxy-phenoxy)-benzoyl]-1,2,3,4-tetr...)
Affinity DataEC50:  167nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164969BDBM50164969((S)-2-(3-Methoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  176nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164990BDBM50164990((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  202nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164997BDBM50164997((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  202nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164975BDBM50164975((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  230nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164970BDBM50164970((R)-2-[3-(Pyridin-2-yloxy)-benzoyl]-1,2,3,4-tetrah...)
Affinity DataEC50:  268nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164982BDBM50164982((R)-2-[3-(4-Trifluoromethyl-phenoxy)-benzoyl]-1,2,...)
Affinity DataEC50:  282nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164972BDBM50164972((R)-2-(3-Benzyl-benzoyl)-1,2,3,4-tetrahydro-isoqui...)
Affinity DataEC50:  291nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164967BDBM50164967((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  292nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164983BDBM50164983(2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoquinol...)
Affinity DataEC50:  294nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164966BDBM50164966((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  314nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164989BDBM50164989((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  336nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164987BDBM50164987((R)-2-(2-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  338nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164978BDBM50164978((R)-2-(3-Phenylsulfanyl-benzoyl)-1,2,3,4-tetrahydr...)
Affinity DataEC50:  394nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50165003BDBM50165003((R)-2-(3-Phenoxy-benzoyl)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataEC50:  420nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50164973BDBM50164973((R)-2-[3-(4-Fluoro-phenoxy)-benzoyl]-1,2,3,4-tetra...)
Affinity DataEC50:  590nMAssay Description:Effective concentration for cellular chloride transport in C127 mouse epithelial cell transfected with recombinant Delta F508 CFTRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed