Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50037577
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  19.9nMAssay Description:Inhibition of [3H]dopamine uptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  51nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50:  95nMAssay Description:Inhibition of [3H]dopamine uptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  122nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  289nMAssay Description:Inhibition of [3H]5-HT uptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  289nMAssay Description:Inhibition of [3H]dopamine uptake in HEK293 cells expressing human dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50:  319nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  367nMAssay Description:Displacement of [125I]-RTI-55 from Dopamine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  433nMAssay Description:Displacement of [125I]RTI-55 from human Serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  462nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50:  480nMAssay Description:Inhibition of [3H]norepinephrine uptake in HEK293 cells expressing human norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50:  788nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50084717((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...)
Affinity DataIC50:  2.99E+3nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50: >7.20E+3nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50:  7.54E+3nMAssay Description:Displacement of [125I]RTI-55 from human Serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50050098((S)-Phenyl-(S)-piperidin-2-yl-acetic acid methyl e...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human Serotonin transporter expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Medical University Of South Carolina

Curated by ChEMBL
LigandPNGBDBM50165211((2R,2'R)-Phenyl-piperidin-2-yl-acetic acid ethyl e...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of [3H]5-HT uptake in HEK293 cells expressing human serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed