Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50016145
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165496BDBM50165496(1-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthalazin-1-ylme...)
Affinity DataIC50: 3.80nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165488BDBM50165488(1-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)m...)
Affinity DataIC50: 4.10nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165486BDBM50165486(KU-58684 | 1-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthal...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165497BDBM50165497(3-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthalazin-1-ylme...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165498BDBM50165498(1-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthalazin-1-ylme...)
Affinity DataIC50: 6.80nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165492BDBM50165492(1-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthalazin-1-ylme...)
Affinity DataIC50: 9.5nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165479BDBM50165479(1-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthalazin-1-ylme...)
Affinity DataIC50: 9.80nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165499BDBM50165499(1-(4-Methoxy-phenyl)-3-methyl-1H-pyrazole-4-carbox...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165478BDBM50165478(1-(3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)phe...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165487BDBM50165487(1-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165485BDBM50165485(2,2,2-Trifluoro-N-[3-(4-oxo-3,4-dihydro-phthalazin...)
Affinity DataIC50: 13nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165472BDBM50165472(1-[2-Chloro-5-(4-oxo-3,4-dihydro-phthalazin-1-ylme...)
Affinity DataIC50: 19nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165477BDBM50165477(N-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...)
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165480BDBM50165480(4-Methyl-2-phenyl-thiazole-5-carboxylic acid [3-(4...)
Affinity DataIC50: 27nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165484BDBM50165484(1-[2-Methoxy-5-(4-oxo-3,4-dihydro-phthalazin-1-ylm...)
Affinity DataIC50: 33nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165474BDBM50165474(Acetic acid 3-(4-oxo-3,4-dihydro-phthalazin-1-ylme...)
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165495BDBM50165495(N-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...)
Affinity DataIC50: 47nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165483BDBM50165483(N-Ethyl-3-(4-oxo-3,4-dihydro-phthalazin-1-ylmethyl...)
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165471BDBM50165471(Cyclopropanecarboxylic acid [3-(4-oxo-3,4-dihydro-...)
Affinity DataIC50: 55nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240980BDBM50240980([2,3']Bithiophenyl-5-carboxylic acid [3-(4-oxo-3,4...)
Affinity DataIC50: 56nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165494BDBM50165494(N-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165481BDBM50165481(N-(3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)phe...)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165493BDBM50165493([3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-pheny...)
Affinity DataIC50: 116nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165489BDBM50165489(4-(3-(2-oxopyrrolidin-1-yl)benzyl)phthalazin-1(2H)...)
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165482BDBM50165482(2-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165490BDBM50165490(4-[3-(3-Methyl-[1,2,4]oxadiazol-5-yl)-benzyl]-2H-p...)
Affinity DataIC50: 189nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165491BDBM50165491(Ethanesulfonic acid [3-(4-oxo-3,4-dihydro-phthalaz...)
Affinity DataIC50: 290nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165473BDBM50165473(N-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...)
Affinity DataIC50: 370nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165475BDBM50165475(1-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...)
Affinity DataIC50: 540nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Horsham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 27660BDBM27660(CHEMBL66761 | 4-benzyl-1,2-dihydrophthalazin-1-one...)
Affinity DataIC50: 770nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed