Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50016166
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50123473(1-[9-(3-Chloro-4-methoxy-benzylamino)-3-ethyl-3H-2...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human Phosphodiesterase 5; IC50 range 0.03-0.3 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165805(4-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165811(7-Benzyl-4-sec-butyl-9-methyl-2-phenyl-7H-3,3a,5,7...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165812(7-Benzyl-4-sec-butyl-9-methyl-2-pyridin-2-yl-7H-3,...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 40nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165826(Phosphoric acid mono-[3-(4-sec-butyl-9-methyl-6-ox...)
Affinity DataIC50: 59nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165810(5-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50: 63nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165822(7-Benzyl-4-(1-ethyl-propyl)-9-methyl-2-phenyl-7H-3...)
Affinity DataIC50: 67nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165818(7-Benzyl-9-methyl-2-phenyl-4-m-tolyl-7H-3,3a,5,7,8...)
Affinity DataIC50: 75nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165814(7-Benzyl-9-methyl-2-phenyl-4-pyridin-2-yl-7H-3,3a,...)
Affinity DataIC50: 81nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165806(7-Benzyl-9-methyl-2,4-diphenyl-7H-3,3a,5,7,8-penta...)
Affinity DataIC50: 81nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165810(5-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165827(7-Benzyl-4-methoxymethyl-9-methyl-2-phenyl-7H-3,3a...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165828(7-Benzyl-9-methyl-4-methylsulfanylmethyl-2-phenyl-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165805(4-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50: 110nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165819(7-Benzyl-4,9-dimethyl-2-phenyl-7H-3,3a,5,7,8-penta...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165808(7-Benzyl-9-methyl-2-phenyl-4-pyridin-3-yl-7H-3,3a,...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165825(Phosphoric acid mono-[3-(4,9-dimethyl-6-oxo-2-phen...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165815(7-Benzyl-4,9-dimethyl-2-pyridin-2-yl-7H-3,3a,5,7,8...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165809((E)-3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydr...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165823(7-Benzyl-4-ethoxymethyl-9-methyl-2-phenyl-7H-3,3a,...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165816(3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50: 430nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165817(7-Benzyl-9-methyl-2-phenyl-4-pyridin-4-ylmethyl-7H...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165809((E)-3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydr...)
Affinity DataIC50: 580nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165816(3-(7-Benzyl-9-methyl-6-oxo-2-phenyl-6,7-dihydro-3,...)
Affinity DataIC50: 590nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165813(2-(4-Amino-phenyl)-7-benzyl-4,9-dimethyl-7H-3,3a,5...)
Affinity DataIC50: 920nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165824(7-Benzyl-9-methyl-4-phenethyl-2-phenyl-7H-3,3a,5,7...)
Affinity DataIC50: 980nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165807(7-(4-Amino-benzyl)-4,9-dimethyl-2-phenyl-7H-3,3a,5...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165807(7-(4-Amino-benzyl)-4,9-dimethyl-2-phenyl-7H-3,3a,5...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165806(7-Benzyl-9-methyl-2,4-diphenyl-7H-3,3a,5,7,8-penta...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165821(7-Cyclohexylmethyl-4,9-dimethyl-2-phenyl-7H-3,3a,5...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165815(7-Benzyl-4,9-dimethyl-2-pyridin-2-yl-7H-3,3a,5,7,8...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165821(7-Cyclohexylmethyl-4,9-dimethyl-2-phenyl-7H-3,3a,5...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165820(2-Benzo[1,3]dioxol-5-yl-7-benzyl-4,9-dimethyl-7H-3...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human Phosphodiesterase 5 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165824(7-Benzyl-9-methyl-4-phenethyl-2-phenyl-7H-3,3a,5,7...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50165820(2-Benzo[1,3]dioxol-5-yl-7-benzyl-4,9-dimethyl-7H-3...)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of bovine Phosphodiesterase 6 (n=2-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed