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Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50037586
TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50326662(10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166216(17-benzyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-...)
Affinity DataKi:  0.120nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50127165(10-hydroxy-17-methoxy-4,13-dimethyl-(13R,17S)-12-o...)
Affinity DataKi:  0.150nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166212(17-ethoxy-10-hydroxy-13-methyl-4-phenethyl-(13R,17...)
Affinity DataKi:  0.160nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166214(10-hydroxy-4-methyl-17-(1-naphthylmethoxy)-(13R,17...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166215(17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166213(17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4...)
Affinity DataKi:  0.610nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166214(10-hydroxy-4-methyl-17-(1-naphthylmethoxy)-(13R,17...)
Affinity DataKi:  0.920nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001707(10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapen...)
Affinity DataKi:  0.970nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166216(17-benzyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-...)
Affinity DataKi:  1.18nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166216(17-benzyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-...)
Affinity DataKi:  2.14nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166215(17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12...)
Affinity DataKi:  2.46nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166214(10-hydroxy-4-methyl-17-(1-naphthylmethoxy)-(13R,17...)
Affinity DataKi:  2.92nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166212(17-ethoxy-10-hydroxy-13-methyl-4-phenethyl-(13R,17...)
Affinity DataKi:  3.14nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166215(17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12...)
Affinity DataKi:  3.67nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50326662(10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  6.55nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50326662(10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...)
Affinity DataKi:  10.2nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166217(17-(2,6-dichlorobenzyloxy)-10-hydroxy-4-methyl-(13...)
Affinity DataKi:  10.3nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50127165(10-hydroxy-17-methoxy-4,13-dimethyl-(13R,17S)-12-o...)
Affinity DataKi:  13.3nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50127165(10-hydroxy-17-methoxy-4,13-dimethyl-(13R,17S)-12-o...)
Affinity DataKi:  25.2nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166217(17-(2,6-dichlorobenzyloxy)-10-hydroxy-4-methyl-(13...)
Affinity DataKi:  33.2nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166213(17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4...)
Affinity DataKi:  33.8nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166213(17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4...)
Affinity DataKi:  36nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001707(10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapen...)
Affinity DataKi:  61.6nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50001707(10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapen...)
Affinity DataKi:  80.5nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166212(17-ethoxy-10-hydroxy-13-methyl-4-phenethyl-(13R,17...)
Affinity DataKi:  83.2nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  113nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166217(17-(2,6-dichlorobenzyloxy)-10-hydroxy-4-methyl-(13...)
Affinity DataKi:  152nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataKi:  217nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166215(17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12...)
Affinity DataIC50:  0.5nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166214(10-hydroxy-4-methyl-17-(1-naphthylmethoxy)-(13R,17...)
Affinity DataIC50:  0.800nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166216(17-benzyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-...)
Affinity DataIC50:  0.900nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166214(10-hydroxy-4-methyl-17-(1-naphthylmethoxy)-(13R,17...)
Affinity DataIC50:  0.900nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166216(17-benzyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-...)
Affinity DataIC50:  1.5nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166212(17-ethoxy-10-hydroxy-13-methyl-4-phenethyl-(13R,17...)
Affinity DataIC50:  1.90nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50326662(10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...)
Affinity DataIC50:  2nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166215(17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12...)
Affinity DataIC50:  2.30nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50127165(10-hydroxy-17-methoxy-4,13-dimethyl-(13R,17S)-12-o...)
Affinity DataIC50:  6.10nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166212(17-ethoxy-10-hydroxy-13-methyl-4-phenethyl-(13R,17...)
Affinity DataIC50:  9.70nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166213(17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4...)
Affinity DataIC50:  17.6nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50127165(10-hydroxy-17-methoxy-4,13-dimethyl-(13R,17S)-12-o...)
Affinity DataIC50:  24.4nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50326662(10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-...)
Affinity DataIC50:  30.5nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166213(17-allyloxy-10-hydroxy-4-methyl-(13R,17S)-12-oxa-4...)
Affinity DataIC50:  63nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166217(17-(2,6-dichlorobenzyloxy)-10-hydroxy-4-methyl-(13...)
Affinity DataIC50:  209nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataIC50:  311nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166217(17-(2,6-dichlorobenzyloxy)-10-hydroxy-4-methyl-(13...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed