Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50016239
LigandChemical structure of BindingDB Monomer ID 50166702BDBM50166702(2-[1-(4-Chloro-benzenesulfonyl)-cyclohexyl]-1,4-di...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166710BDBM50166710(4-(4-Chloro-benzenesulfonyl)-4-(2,5-difluoro-pheny...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166710BDBM50166710(4-(4-Chloro-benzenesulfonyl)-4-(2,5-difluoro-pheny...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166696BDBM50166696(3-(4-Chloro-benzenesulfonyl)-3-(2,5-difluoro-pheny...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166696BDBM50166696(3-(4-Chloro-benzenesulfonyl)-3-(2,5-difluoro-pheny...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166709BDBM50166709(4-(4-Chloro-benzenesulfonyl)-4-(2,5-difluoro-pheny...)
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166703BDBM50166703(4-Chloro-N-(2,5-difluoro-phenyl)-N-((R)-2-hydroxy-...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166699BDBM50166699(4-(4-Chloro-benzenesulfonyl)-4-(2,5-difluoro-pheny...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166704BDBM50166704(1-{1-[(4-chlorophenyl)sulfonyl]cyclohexyl}-2-fluor...)
Affinity DataIC50: 55nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166698BDBM50166698(2-[1-(4-Chloro-benzenesulfonyl)-2-methyl-propyl]-1...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166705BDBM50166705(2-(1-Benzenesulfonyl-cyclohexyl)-1,4-difluoro-benz...)
Affinity DataIC50: 98nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166708BDBM50166708(5-(4-Chloro-benzenesulfonyl)-5-(2,5-difluoro-pheny...)
Affinity DataIC50: 104nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166707BDBM50166707(4-Chloro-N-(2,5-difluoro-phenyl)-N-isopropyl-benze...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166706BDBM50166706(1-{1-[(4-chlorophenyl)sulfonyl]cyclohexyl}-3-fluor...)
Affinity DataIC50: 249nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166697BDBM50166697(3-(4-Chloro-benzenesulfonyl)-3-(2,5-difluoro-pheny...)
Affinity DataIC50: 253nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166713BDBM50166713(3-(4-Chloro-benzenesulfonyl)-3-(2,5-difluoro-pheny...)
Affinity DataIC50: 304nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166714BDBM50166714(1-Chloro-4-(1-phenyl-cyclohexanesulfonyl)-benzene ...)
Affinity DataIC50: 461nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166701BDBM50166701(4-Chloro-N-(2,5-difluoro-phenyl)-N-methyl-benzenes...)
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166712BDBM50166712(2-[1-(4-Chloro-benzenesulfonyl)-ethyl]-1,4-difluor...)
Affinity DataIC50: 2.47E+3nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166711BDBM50166711(2-(4-Chloro-benzenesulfonylmethyl)-1,4-difluoro-be...)
Affinity DataIC50: 4.41E+3nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50166700BDBM50166700(4-Chloro-N-(2,5-difluoro-phenyl)-benzenesulfonamid...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed