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Found 42 Enz. Inhib. hit(s) with all data for entry = 50037390
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166817(3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phen...)
Affinity DataIC50:  9nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166820(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  13nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166821(3-[2-Ethoxy-5-(4-isopropyl-piperazine-1-sulfonyl)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  25nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166822(6-Bromo-3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfo...)
Affinity DataIC50:  33nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166824(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  38nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166818(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  48nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166816(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  80nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166827(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  112nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166825(3-(2-Ethoxy-phenyl)-5-methyl-2H-2,4,4b,9-tetraaza-...)
Affinity DataIC50:  116nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166819(6-Bromo-3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfo...)
Affinity DataIC50:  146nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166820(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  184nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166817(3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phen...)
Affinity DataIC50:  204nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166821(3-[2-Ethoxy-5-(4-isopropyl-piperazine-1-sulfonyl)-...)
Affinity DataIC50:  275nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166822(6-Bromo-3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfo...)
Affinity DataIC50:  289nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166830(3-(2-Ethoxy-phenyl)-6-methyl-2H-2,4,4b,9-tetraaza-...)
Affinity DataIC50:  381nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166824(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  455nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166816(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  472nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  561nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166826(3-(2-Ethoxy-phenyl)-5-ethyl-2H-2,4,4b,9-tetraaza-f...)
Affinity DataIC50:  634nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166818(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  693nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166829(6-Bromo-3-(2-ethoxy-phenyl)-5-methyl-2H-2,4,4b,9-t...)
Affinity DataIC50:  710nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166837(3-(2-Ethoxy-phenyl)-7-methyl-2H-2,4,4b,9-tetraaza-...)
Affinity DataIC50:  849nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166819(6-Bromo-3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfo...)
Affinity DataIC50:  860nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370451(CHEMBL554480)
Affinity DataIC50:  878nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166832(3-(2-Ethoxy-phenyl)-8-methyl-2H-2,4,4b,9-tetraaza-...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166827(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166834(3-(2-Ethoxy-phenyl)-5-pyrrolidin-1-ylmethyl-2H-2,4...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166836(3-(2-Ethoxy-phenyl)-5-(4-methyl-piperazin-1-ylmeth...)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166833(6,8-Dibromo-3-(2-ethoxy-phenyl)-5-methyl-2H-2,4,4b...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166828(6-Bromo-3-(2-ethoxy-phenyl)-2H-2,4,4b,9-tetraaza-f...)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166831(3-(2-Ethoxy-phenyl)-1-oxo-1,2-dihydro-2,4,4b,9-tet...)
Affinity DataIC50:  3.34E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166838(3-(2-Ethoxy-phenyl)-5-methyl-1-oxo-1,2-dihydro-2,4...)
Affinity DataIC50:  4.87E+3nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50370451(CHEMBL554480)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibition of phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50166835(3-(2-Ethoxy-phenyl)-2H-2,4,4b,9-tetraaza-fluoren-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of phosphodiesterase 5 isolated from human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50166824(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50166820(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50166821(3-[2-Ethoxy-5-(4-isopropyl-piperazine-1-sulfonyl)-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50166817(3-[2-Ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50166822(6-Bromo-3-[2-ethoxy-5-(4-methyl-piperazine-1-sulfo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50166818(3-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of phosphodiesterase 1 isolated from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed