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Report error Found 83 Enz. Inhib. hit(s) with all data for entry = 50000470
TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006189((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  0.900nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006206(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006185(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006152(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006161(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  1.10nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006211(CHEMBL49218 | {4-[2-(2-tert-Butoxycarbonylamino-3-...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006204(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006208(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006176(CHEMBL264194 | {4-[2-(2-tert-Butoxycarbonylamino-3...)
Affinity DataIC50:  1.30nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006197(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.40nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006195((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  1.40nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006184((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  1.5nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006196((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  1.5nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006148(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.5nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006207(CHEMBL301395 | {4-[2-(2-tert-Butoxycarbonylamino-3...)
Affinity DataIC50:  1.70nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006157(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  1.80nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006200((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  1.80nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006179((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50:  2nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006192(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  2.10nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006183((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  2.20nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006202(3-Amino-N-[1-[1-(1-cyclohexylmethyl-2,3-dihydroxy-...)
Affinity DataIC50:  2.30nMpH: 7.7Assay Description:Inhibitory activity against renin in monkey plasma at pH 7.7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006213(CHEMBL48343 | {4-[2-(2-tert-Butoxycarbonylamino-3-...)
Affinity DataIC50:  2.30nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006187((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50:  2.40nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006205((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  2.40nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006177(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  2.40nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006182((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  2.5nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006186(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  2.5nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006181(CHEMBL299605 | {4-[2-(2-tert-Butoxycarbonylamino-3...)
Affinity DataIC50:  2.70nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006191((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  2.70nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006214(CHEMBL297701 | {1-[1-[1-Cyclohexylmethyl-2-hydroxy...)
Affinity DataIC50:  2.70nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006187((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50:  2.80nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006201(CHEMBL48722 | {4-[2-(2-tert-Butoxycarbonylamino-3-...)
Affinity DataIC50:  2.80nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006180(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  2.90nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006208(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  3nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006210(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  3.20nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006198((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50:  3.30nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006204(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  3.5nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006185(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  3.70nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006178(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  4.30nMpH: 6.0Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006176(CHEMBL264194 | {4-[2-(2-tert-Butoxycarbonylamino-3...)
Affinity DataIC50:  4.70nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006197(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  5nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006212((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  5nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006206(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  5.10nMpH: 7.4Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006210(2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)-2-...)
Affinity DataIC50:  5.30nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006180(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  5.70nMpH: 7.4Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006186(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  5.90nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006194(CHEMBL48481 | {1-[1-(1-Cyclohexylmethyl-2-hydroxy-...)
Affinity DataIC50:  6nMpH: 6.0Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006192(5-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl)...)
Affinity DataIC50:  6.10nMpH: 7.4Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006198((2S,4S,5S)-5-{(S)-2-[(S)-1-Benzyl-2-(4-methoxymeth...)
Affinity DataIC50:  7.30nMpH: 7.4Assay Description:In vitro potency against human plasma renin at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetRenin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50006195((4-{2-[1-Benzyl-2-(4-methoxymethoxy-piperidin-1-yl...)
Affinity DataIC50:  7.5nMpH: 7.4Assay Description:In vitro activity against human renin (pH 6.0)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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