Compile Data Set for Download or QSAR
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Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 2211
TargetGlutamate--tRNA ligase(Escherichia coli (strain K12))
Crefsip

LigandPNGBDBM18122((4S)-4-amino-5-[({[(2R,3S,4R,5R)-5-(6-amino-9H-pur...)
Affinity DataKi:  2.80nM ΔG°:  -50.8kJ/molepH: 7.2 T: 37°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM18122((4S)-4-amino-5-[({[(2R,3S,4R,5R)-5-(6-amino-9H-pur...)
Affinity DataKi:  70nM ΔG°:  -41.5kJ/molepH: 8.0 T: 30°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlutamate--tRNA ligase(Escherichia coli (strain K12))
Crefsip

LigandPNGBDBM18123((5S)-5-{[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl...)
Affinity DataKi:  1.50E+4nM ΔG°:  -28.6kJ/molepH: 7.2 T: 37°CAssay Description:The Km and Kappm for the amino acid substrate were first calculated from Lineweaver-Burk plots. The Ki values were calculated from the Kappm vs [I] p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed