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Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50016335
TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167861(CHEMBL196715 | N-(4-Iodo-benzo[b]thiophene-2-carbo...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167865(CHEMBL195422 | N-(4-Chloro-benzo[b]thiophene-2-car...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167856(CHEMBL197401 | N-(4-Bromo-benzo[b]thiophene-2-carb...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167841(CHEMBL196790 | N-(4-Ethyl-benzo[b]thiophene-2-carb...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167846(CHEMBL425378 | N-(4-Vinyl-benzo[b]thiophene-2-carb...)
Affinity DataIC50:  310nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167845(CHEMBL197519 | N-(4-Trifluoromethyl-benzo[b]thioph...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167863(CHEMBL196487 | N-(4-Methyl-benzo[b]thiophene-2-car...)
Affinity DataIC50:  480nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167867(CHEMBL425565 | N-[4-(3,5-Dichloro-phenyl)-benzo[b]...)
Affinity DataIC50:  680nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50058759(CHEMBL436559 | CHEMBL462831 | Cariporide | N-(4-Is...)
Affinity DataIC50:  680nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167839(CHEMBL193812 | N-(4-Isopropyl-benzo[b]thiophene-2-...)
Affinity DataIC50:  850nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167852(CHEMBL196714 | N-(4-Fluoro-benzo[b]thiophene-2-car...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167868(CHEMBL371454 | N-(4-Cyano-benzo[b]thiophene-2-carb...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167847(CHEMBL197156 | N-(4-Nitro-benzo[b]thiophene-2-carb...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167850(CHEMBL193499 | N-[4-(3-Chloro-phenyl)-benzo[b]thio...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167866(CHEMBL193701 | N-[4-(3-Chloro-4-fluoro-phenyl)-ben...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167843(CHEMBL197155 | N-(4-Methoxy-benzo[b]thiophene-2-ca...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167848(CHEMBL372839 | N-(4-m-Tolyl-benzo[b]thiophene-2-ca...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167840(CHEMBL197409 | N-[4-(4-Fluoro-phenyl)-benzo[b]thio...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167851(CHEMBL370216 | N-[4-(2-Chloro-phenyl)-benzo[b]thio...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167857(CHEMBL195986 | N-[4-(3-Trifluoromethyl-phenyl)-ben...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167844(CHEMBL263960 | N-[4-(3,5-Difluoro-phenyl)-benzo[b]...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167842(CHEMBL436285 | N-[4-(3-Fluoro-phenyl)-benzo[b]thio...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167862(CHEMBL196655 | N-(4-o-Tolyl-benzo[b]thiophene-2-ca...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167864(CHEMBL197147 | N-(4-Phenyl-benzo[b]thiophene-2-car...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167849(CHEMBL195507 | N-[4-(2,5-Difluoro-phenyl)-benzo[b]...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167858(CHEMBL196066 | N-[4-(2,3-Difluoro-phenyl)-benzo[b]...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167855(CHEMBL193941 | N-[4-(3-Methoxy-phenyl)-benzo[b]thi...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167860(CHEMBL196943 | N-[4-(2-Fluoro-phenyl)-benzo[b]thio...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167838(CHEMBL196645 | N-(Benzo[b]thiophene-2-carbonyl)-gu...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167859(CHEMBL427551 | N-(4-Amino-benzo[b]thiophene-2-carb...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167854(CHEMBL372360 | N-(4-p-Tolyl-benzo[b]thiophene-2-ca...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium/hydrogen exchanger 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50167853(CHEMBL194606 | N-[4-(4-Chloro-phenyl)-benzo[b]thio...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against human sodium/hydrogen exchanger (NHE-1) in PS120 variant cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed