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Found 36 Enz. Inhib. hit(s) with all data for entry = 50016443
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)
Affinity DataKi:  0.0130nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)
Affinity DataKi:  0.25nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169004(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-ethyl-p...)
Affinity DataKi:  0.490nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465(CHEMBL190937 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi:  0.570nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169010(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-vinyl-p...)
Affinity DataKi:  1.12nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169009(2-(2-Dimethylaminomethyl-phenylsulfanyl)-phenylami...)
Affinity DataKi:  1.59nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169006(5-Ethyl-2-(2-methylaminomethyl-phenylsulfanyl)-phe...)
Affinity DataKi:  2.04nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169009(2-(2-Dimethylaminomethyl-phenylsulfanyl)-phenylami...)
Affinity DataKi:  4.95nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi:  8.5nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi:  8.55nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169008(CHEMBL362783 | [3-Amino-4-(2-methylaminomethyl-phe...)
Affinity DataKi:  15.1nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169011(2-[3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl...)
Affinity DataKi:  50.6nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)
Affinity DataKi:  61nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169007(3-[3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl...)
Affinity DataKi:  92.3nMAssay Description:In vitro inhibition of [3H]-citalopram binding to human serotonin transporter expressed in human HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169007(3-[3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl...)
Affinity DataKi:  108nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169011(2-[3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl...)
Affinity DataKi:  194nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi:  219nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169010(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-vinyl-p...)
Affinity DataKi:  269nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169009(2-(2-Dimethylaminomethyl-phenylsulfanyl)-phenylami...)
Affinity DataKi:  279nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465(CHEMBL190937 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi:  303nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169004(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-ethyl-p...)
Affinity DataKi:  370nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169006(5-Ethyl-2-(2-methylaminomethyl-phenylsulfanyl)-phe...)
Affinity DataKi:  445nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169008(CHEMBL362783 | [3-Amino-4-(2-methylaminomethyl-phe...)
Affinity DataKi:  484nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50110788(2-(2-((dimethylamino)methyl)phenylthio)-5-methylan...)
Affinity DataKi:  532nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)
Affinity DataKi:  699nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)
Affinity DataKi:  840nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169010(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-vinyl-p...)
Affinity DataKi:  962nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164465(CHEMBL190937 | N,N-dimethyl-2-(2'-amino-4'-hydroxy...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169008(CHEMBL362783 | [3-Amino-4-(2-methylaminomethyl-phe...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169006(5-Ethyl-2-(2-methylaminomethyl-phenylsulfanyl)-phe...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169011(2-[3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169004(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-ethyl-p...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi: >5.00E+3nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164466(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(2-fluo...)
Affinity DataKi: >5.00E+3nMAssay Description:In vitro inhibition of [3H]-nisoxetine binding to norepinephrine transporter expressed in human kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50164473(2-(2-Dimethylaminomethyl-phenylsulfanyl)-5-(3-fluo...)
Affinity DataKi: >5.00E+3nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50169007(3-[3-Amino-4-(2-dimethylaminomethyl-phenylsulfanyl...)
Affinity DataKi: >5.00E+3nMAssay Description:In vitro inhibition of [3H]-WIN- 35,428 binding to human dopamine transporter expressed in canine kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed