Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 1528
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11928BDBM11928((1S,3S,5S)-2-{[(2S,4S)-4-[(3-chloro-4-cyanophenyl)...)
Affinity DataKi:  3.60nM ΔG°:  -47.7kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11920BDBM11920((1S,3S,5S)-2-{[(2S)-3,3-dimethylpyrrolidin-2-yl]ca...)
Affinity DataKi:  37nM ΔG°:  -42.0kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11927BDBM11927(4-chloro-N-[(3S,5S)-5-{[(1S,3S,5S)-3-cyano-2-azabi...)
Affinity DataKi:  39nM ΔG°:  -41.9kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11917BDBM11917((1S,3S,5S)-2-[(1S,2S,5R)-3-azabicyclo[3.1.0]hexan-...)
Affinity DataKi:  52nM ΔG°:  -41.2kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11925BDBM11925(9H-fluoren-9-ylmethyl N-[(3S,5S)-5-{[(1S,3S,5S)-3-...)
Affinity DataKi:  57nM ΔG°:  -40.9kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11919BDBM11919((1S,3S,5S)-2-{[(2S,3S)-3-methylpyrrolidin-2-yl]car...)
Affinity DataKi:  126nM ΔG°:  -39.0kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11926BDBM11926(N-[(3S,5S)-5-{[(1S,3S,5S)-3-cyano-2-azabicyclo[3.1...)
Affinity DataKi:  133nM ΔG°:  -38.9kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11923BDBM11923(tert-butyl N-[(3S,5S)-5-{[(1S,3S,5S)-3-cyano-2-aza...)
Affinity DataKi:  140nM ΔG°:  -38.7kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11921BDBM11921((1S,3S,5S)-2-{[(2S,3S)-3-ethylpyrrolidin-2-yl]carb...)
Affinity DataKi:  290nM ΔG°:  -36.9kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11914BDBM11914((1S,3S,5S)-2-[(2S)-pyrrolidin-2-ylcarbonyl]-2-azab...)
Affinity DataKi:  305nM ΔG°:  -36.8kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11924BDBM11924(tert-butyl N-[(3R,5S)-5-{[(1S,3S,5S)-3-cyano-2-aza...)
Affinity DataKi:  492nM ΔG°:  -35.6kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11922BDBM11922((1S,3S,5S)-2-{[(2S,3R)-3-(propan-2-yl)pyrrolidin-2...)
Affinity DataKi:  695nM ΔG°:  -34.8kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11915BDBM11915((1S,3S,5S)-2-[(2R)-pyrrolidin-2-ylcarbonyl]-2-azab...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11916BDBM11916((1S,3S,5S)-2-[(2S)-azetidin-2-ylcarbonyl]-2-azabic...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11918BDBM11918((1S,3S,5S)-2-[(1S,3S,5S)-2-azabicyclo[3.1.0]hexan-...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandChemical structure of BindingDB Monomer ID 11913BDBM11913((1S,3S,5S)-2-[(2S)-piperidin-2-ylcarbonyl]-2-azabi...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed