Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 3064
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27525(N-[3-(morpholin-4-yl)propyl]-8-oxo-9-azatetracyclo...)
Affinity DataIC50:  1nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27528(13-fluoro-N-[3-(morpholin-4-yl)propyl]-8-oxo-9-aza...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27521(2-[4-(4-fluorophenyl)piperazin-1-yl]-N-{8-oxo-9-az...)
Affinity DataIC50:  80nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27515(14-amino-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50:  98nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27524(1-{8-oxo-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50:  100nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27522(4-(morpholin-4-yl)-N-{8-oxo-9-azatetracyclo[8.7.0....)
Affinity DataIC50:  105nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27520(2-(dimethylamino)-N-{8-oxo-9-azatetracyclo[8.7.0.0...)
Affinity DataIC50:  107nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27523(2-hydroxy-N-{8-oxo-9-azatetracyclo[8.7.0.0^{2,7}.0...)
Affinity DataIC50:  110nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27514(13-amino-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50:  300nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27511(14-nitro-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50:  300nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27526(N-[3-(1H-imidazol-1-yl)propyl]-8-oxo-9-azatetracyc...)
Affinity DataIC50:  394nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27519(4-(morpholin-4-yl)-N-{8-oxo-9-azatetracyclo[8.7.0....)
Affinity DataIC50:  400nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27529(13-fluoro-N-(morpholin-4-yl)-8-oxo-9-azatetracyclo...)
Affinity DataIC50:  450nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27512(13-fluoro-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]...)
Affinity DataIC50:  500nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27510(13-nitro-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50:  500nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27530(13-fluoro-14-(1H-imidazole-1-sulfonyl)-9-azatetrac...)
Affinity DataIC50:  500nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27513(14-fluoro-9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]...)
Affinity DataIC50:  650nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27531(indeno[1,2-c]isoquinolinone, 13 | sodium 8-oxo-9-a...)
Affinity DataIC50:  700nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27532(4-methyl-4-[3-({8-oxo-9-azatetracyclo[8.7.0.0^{2,7...)
Affinity DataIC50:  800nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27516(2-(dimethylamino)-N-{8-oxo-9-azatetracyclo[8.7.0.0...)
Affinity DataIC50:  800nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27518(2-(4-methylpiperazin-1-yl)-N-{8-oxo-9-azatetracycl...)
Affinity DataIC50: >3.00E+3nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27527(8-oxo-N-(3-phenylpropyl)-9-azatetracyclo[8.7.0.0^{...)
Affinity DataIC50: >3.00E+3nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27508(9-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-...)
Affinity DataIC50: >3.00E+3nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27517(2-(morpholin-4-yl)-N-{8-oxo-9-azatetracyclo[8.7.0....)
Affinity DataIC50: >3.00E+3nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Inotek Pharmaceuticals

LigandPNGBDBM27506(3-AB | 3-aminobenzamide | CHEMBL81977)
Affinity DataIC50:  3.00E+4nMpH: 8.0 T: 2°CAssay Description:The potency of inhibition on purified PARP enzyme was determined for selected compounds, and the potency was compared with that of 3-aminobenzamide (...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed