Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50003721
TargetDNA gyrase subunit B(Staphylococcus aureus subsp. aureus Mu50)
Wockhardt

Curated by ChEMBL
LigandPNGBDBM50475221(CHEMBL187677)
Affinity DataIC50: 8.24E+3nMAssay Description:Inhibition of supercoiling activity of DNA gyrase from Staphylococcus aureus ISP 794; Range = 2.5-5 ug/mLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Wockhardt

Curated by ChEMBL
LigandPNGBDBM50475221(CHEMBL187677)
Affinity DataIC50: 8.24E+3nMAssay Description:Inhibition of supercoiling activity of topoisomerase IV from Staphylococcus aureus ISP 794More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Wockhardt

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of supercoiling activity of topoisomerase IV from Staphylococcus aureus ISP 794; Range = 2.5-5 ug/mLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus subsp. aureus Mu50)
Wockhardt

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of supercoiling activity of DNA gyrase from Staphylococcus aureus ISP 794More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit B(Staphylococcus aureus subsp. aureus Mu50)
Wockhardt

Curated by ChEMBL
LigandPNGBDBM50475222(CHEBI:31889 | Nadifloxacin | OPC 7251 | OPC-7251)
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibition of supercoiling activity of DNA gyrase from Staphylococcus aureus ISP 794More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 4 subunit A(Staphylococcus aureus)
Wockhardt

Curated by ChEMBL
LigandPNGBDBM50475222(CHEBI:31889 | Nadifloxacin | OPC 7251 | OPC-7251)
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibition of supercoiling activity of topoisomerase IV from Staphylococcus aureus ISP 794More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed