Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50016747
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17967BDBM17967(CHEMBL411885 | N-[2-(7-{[(2R)-1-(4-{3-[(2-methoxyp...)
Affinity DataIC50: 0.400nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173065BDBM50173065((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173069BDBM50173069((R)-6-(4-Chloro-3-trifluoromethyl-benzyloxymethyl)...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173076BDBM50173076((R)-6-(4-Fluoro-3-trifluoromethyl-benzyloxymethyl)...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173067BDBM50173067((R)-6-(3,5-Dichloro-benzyloxymethyl)-1-{4-[3-(2-me...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173063BDBM50173063((R)-6-(3,4-Dichloro-benzyloxymethyl)-1-{4-[3-(2-me...)
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173074BDBM50173074((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173085BDBM50173085((R)-6-(2-Fluoro-benzyloxymethyl)-1-{4-[3-(2-methox...)
Affinity DataIC50: 230nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173079BDBM50173079((R)-6-(3,4-Difluoro-benzyloxymethyl)-1-{4-[3-(2-me...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173078BDBM50173078((R)-6-(3-Chloro-4-methyl-benzyloxymethyl)-1-{4-[3-...)
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173081BDBM50173081((R)-6-(2-Fluoro-3-trifluoromethyl-benzyloxymethyl)...)
Affinity DataIC50: 270nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173089BDBM50173089((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 270nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173086BDBM50173086((R)-6-(4-Fluoro-3-methyl-benzyloxymethyl)-1-{4-[3-...)
Affinity DataIC50: 270nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173071BDBM50173071((R)-6-(4-Chloro-benzyloxymethyl)-1-{4-[3-(2-methox...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173080BDBM50173080((R)-6-(3-Chloro-benzyloxymethyl)-1-{4-[3-(2-methox...)
Affinity DataIC50: 330nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173073BDBM50173073((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 340nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173066BDBM50173066((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 370nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173077BDBM50173077((R)-6-(2-Chloro-4-fluoro-benzyloxymethyl)-1-{4-[3-...)
Affinity DataIC50: 410nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173075BDBM50173075((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 410nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173082BDBM50173082((R)-6-(4-Fluoro-benzyloxymethyl)-1-{4-[3-(2-methox...)
Affinity DataIC50: 450nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173083BDBM50173083((S)-6-(4-Chloro-3-trifluoromethyl-benzyloxymethyl)...)
Affinity DataIC50: 594nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173072BDBM50173072((R)-6-(3-Methoxy-benzyloxymethyl)-1-{4-[3-(2-metho...)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173060BDBM50173060((R)-6-(2-Methoxy-benzyloxymethyl)-1-{4-[3-(2-metho...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173062BDBM50173062((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173087BDBM50173087((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173061BDBM50173061(3-((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phen...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173059BDBM50173059((R)-6-(3,5-Difluoro-benzyloxymethyl)-1-{4-[3-(2-me...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173068BDBM50173068((R)-6-(4-Methoxy-benzyloxymethyl)-1-{4-[3-(2-metho...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173064BDBM50173064((S)-6-(4-Fluoro-benzyloxymethyl)-1-{4-[3-(2-methox...)
Affinity DataIC50: 5.59E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173084BDBM50173084((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173070BDBM50173070((R)-6-Benzyloxymethyl-1-{4-[3-(2-methoxy-benzyloxy...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173088BDBM50173088((S)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed