Compile Data Set for Download or QSAR
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Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50016773
TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173461(4-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-ylami...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173454(4-(1-Benzooxazol-5-ylmethyl-piperidin-4-ylamino)-6...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173465(6-Methoxy-4-[1-(3-phenyl-allyl)-piperidin-4-ylamin...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173452(4-(1-Benzo[b]thiophen-5-ylmethyl-piperidin-4-ylami...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173459(6-Chloro-4-[1-(1H-indol-5-ylmethyl)-piperidin-4-yl...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173464(6-Chloro-4-[1-(3-phenyl-allyl)-piperidin-4-ylamino...)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173460(4-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50:  11nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173453(6-Chloro-4-[1-(2,2-difluoro-benzo[1,3]dioxol-5-ylm...)
Affinity DataIC50:  19nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173458(6-Chloro-4-(1-naphthalen-2-ylmethyl-piperidin-4-yl...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173456(6-Chloro-4-[1-(1H-indol-6-ylmethyl)-piperidin-4-yl...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173462(6-Chloro-4-[1-(2,3-dihydro-benzofuran-5-ylmethyl)-...)
Affinity DataIC50:  27nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173461(4-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-ylami...)
Affinity DataIC50:  28nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173456(6-Chloro-4-[1-(1H-indol-6-ylmethyl)-piperidin-4-yl...)
Affinity DataIC50:  28nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173462(6-Chloro-4-[1-(2,3-dihydro-benzofuran-5-ylmethyl)-...)
Affinity DataIC50:  41nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173465(6-Methoxy-4-[1-(3-phenyl-allyl)-piperidin-4-ylamin...)
Affinity DataIC50:  44nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173455(6-Chloro-4-[1-(1-methyl-1H-indol-6-ylmethyl)-piper...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173459(6-Chloro-4-[1-(1H-indol-5-ylmethyl)-piperidin-4-yl...)
Affinity DataIC50:  63nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173463(4-(1-Benzooxazol-6-ylmethyl-piperidin-4-ylamino)-6...)
Affinity DataIC50:  75nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173458(6-Chloro-4-(1-naphthalen-2-ylmethyl-piperidin-4-yl...)
Affinity DataIC50:  92nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173455(6-Chloro-4-[1-(1-methyl-1H-indol-6-ylmethyl)-piper...)
Affinity DataIC50:  162nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173454(4-(1-Benzooxazol-5-ylmethyl-piperidin-4-ylamino)-6...)
Affinity DataIC50:  163nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173452(4-(1-Benzo[b]thiophen-5-ylmethyl-piperidin-4-ylami...)
Affinity DataIC50:  189nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173457(4-{1-[((E)-3-Phenyl)-allyl]-piperidin-4-ylamino}-c...)
Affinity DataIC50:  191nMAssay Description:Inhibitory concentration aganist melanin concentrating hormone receptor 1 expressed in IMR-32 cells using [125I]-MCHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173464(6-Chloro-4-[1-(3-phenyl-allyl)-piperidin-4-ylamino...)
Affinity DataIC50:  211nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173463(4-(1-Benzooxazol-6-ylmethyl-piperidin-4-ylamino)-6...)
Affinity DataIC50:  461nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173453(6-Chloro-4-[1-(2,2-difluoro-benzo[1,3]dioxol-5-ylm...)
Affinity DataIC50:  581nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173457(4-{1-[((E)-3-Phenyl)-allyl]-piperidin-4-ylamino}-c...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173461(4-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-4-ylami...)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of human potassium channel HERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50173466(4-[1-(4-tert-Butyl-benzyl)-piperidin-4-ylamino]-6-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of melanin concentrating hormone receptor 1 mediated [Ca2+] release in IMR-32 cells in Ca+2 release cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed