Compile Data Set for Download or QSAR
maximum 50k data
Found 47 Enz. Inhib. hit(s) with all data for entry = 50016840
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174251((S)-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-ph...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174243((R)-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-ph...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174233(CHEMBL373037 | N-((R)-1-(4-chloro-benzyl)-2-oxo-2-...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174256(3-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataKi:  42nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174237((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  60nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174232((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  61nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174253(2-amino-N-((R)-1-(4-chloro-benzyl)-2-oxo-2-{4-[1-(...)
Affinity DataKi:  79nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174259(CHEMBL197435 | N-((R)-1-(4-chloro-benzyl)-2-oxo-2-...)
Affinity DataKi:  80nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174250(2-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataKi:  82nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174239((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  84nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174244((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  97nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174242(CHEMBL433991 | N-((R)-3-(4-chlorophenyl)-1-oxo-1-(...)
Affinity DataKi:  99nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174262((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  100nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174254(CHEMBL199061 | N-((R)-1-(4-chloro-benzyl)-2-oxo-2-...)
Affinity DataKi:  100nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174238(CHEMBL371683 | N-(1-{4-[(R)-2-acetylamino-3-(4-chl...)
Affinity DataKi:  110nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174248(2-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataKi:  120nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174263((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  130nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174246(2-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataKi:  130nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174257((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  140nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174234((R)-2-amino-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataKi:  140nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174258((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  150nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174231((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  160nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174252(CHEMBL199273 | N-((R)-1-(4-chloro-benzyl)-2-oxo-2-...)
Affinity DataKi:  170nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174235(CHEMBL372621 | N-((R)-1-(4-Chloro-benzyl)-2-oxo-2-...)
Affinity DataKi:  180nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174240(CHEMBL197278 | N-((R)-3-(4-chlorophenyl)-1-oxo-1-(...)
Affinity DataKi:  210nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174261((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  210nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174245((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  230nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174249(1-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataKi:  260nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174241((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  270nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174255((R)-isobutyl 3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-...)
Affinity DataKi:  280nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174247((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  300nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174236((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  750nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174260((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174249(1-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataEC50:  810nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174248(2-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataEC50:  590nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174251((S)-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-ph...)
Affinity DataEC50:  46nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174250(2-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataEC50:  160nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174254(CHEMBL199061 | N-((R)-1-(4-chloro-benzyl)-2-oxo-2-...)
Affinity DataEC50:  300nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174234((R)-2-amino-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataEC50:  280nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174233(CHEMBL373037 | N-((R)-1-(4-chloro-benzyl)-2-oxo-2-...)
Affinity DataEC50:  37nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174242(CHEMBL433991 | N-((R)-3-(4-chlorophenyl)-1-oxo-1-(...)
Affinity DataEC50:  440nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174256(3-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataEC50:  270nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174243((R)-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-ph...)
Affinity DataEC50:  33nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174240(CHEMBL197278 | N-((R)-3-(4-chlorophenyl)-1-oxo-1-(...)
Affinity DataEC50:  360nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174253(2-amino-N-((R)-1-(4-chloro-benzyl)-2-oxo-2-{4-[1-(...)
Affinity DataEC50:  530nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174236((R)-N-(3-(4-chlorophenyl)-1-oxo-1-(4-(1-((2-phenyl...)
Affinity DataEC50:  570nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50174246(2-amino-N-((R)-3-(4-chlorophenyl)-1-oxo-1-(4-(1-((...)
Affinity DataEC50:  420nMAssay Description:cAMP stimulation in HEK293 cells transfected with human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed