Compile Data Set for Download or QSAR
maximum 50k data
Found 62 Enz. Inhib. hit(s) with all data for entry = 50016892
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174908(CHEMBL427367 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  5nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174921(CHEMBL196973 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  6nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174920(CHEMBL199025 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  7nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174919(CHEMBL371222 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  8nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174913(CHEMBL197232 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  9nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174895((1-benzo{1,3}dioxol-5-ylmethyl-piperidin-4-yl)(5-c...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174893(CHEMBL197497 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174916(5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-y...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174911(1-(3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174906((3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174899((3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174892(CHEMBL381013 | N-(1-((2,3-dihydrobenzo[b][1,4]diox...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174915(CHEMBL199222 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174904((3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174901(5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-y...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174897(CHEMBL370576 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  40nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174914(CHEMBL197395 | N-(1-(benzo[c][1,2,5]thiadiazol-5-y...)
Affinity DataIC50:  50nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174912(CHEMBL198789 | N-(1-((1H-indazol-6-yl)methyl)piper...)
Affinity DataIC50:  50nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174909(CHEMBL370361 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  50nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174919(CHEMBL371222 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  60nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174905(5-chloro-N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-y...)
Affinity DataIC50:  70nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174921(CHEMBL196973 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  70nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174894(CHEMBL197283 | N-(1-(3,4-dimethylbenzyl)piperidin-...)
Affinity DataIC50:  100nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174896(CHEMBL196972 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  110nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174900(CHEMBL197281 | N-(1-(3-methoxybenzyl)piperidin-4-y...)
Affinity DataIC50:  150nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174915(CHEMBL199222 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  190nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174903(CHEMBL370360 | N-(1-(4-chlorobenzyl)piperidin-4-yl...)
Affinity DataIC50:  200nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174910(3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50:  220nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174898(CHEMBL197058 | N-(1-(2-fluoro-4-methoxybenzyl)pipe...)
Affinity DataIC50:  240nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174895((1-benzo{1,3}dioxol-5-ylmethyl-piperidin-4-yl)(5-c...)
Affinity DataIC50:  260nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174917(5-chloro-N-(1-((7-methoxybenzo[d][1,3]dioxol-5-yl)...)
Affinity DataIC50:  280nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174893(CHEMBL197497 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  290nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174891(CHEMBL198692 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  330nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174908(CHEMBL427367 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  350nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174912(CHEMBL198789 | N-(1-((1H-indazol-6-yl)methyl)piper...)
Affinity DataIC50:  380nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174907(CHEMBL197023 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  440nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174892(CHEMBL381013 | N-(1-((2,3-dihydrobenzo[b][1,4]diox...)
Affinity DataIC50:  520nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174913(CHEMBL197232 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  550nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174920(CHEMBL199025 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  560nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174916(5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-y...)
Affinity DataIC50:  640nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174918(CHEMBL197485 | N-(1-benzylpiperidin-4-yl)-5-chloro...)
Affinity DataIC50:  850nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174906((3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-...)
Affinity DataIC50:  930nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174896(CHEMBL196972 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50:  1.06E+3nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174911(1-(3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-...)
Affinity DataIC50:  1.14E+3nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174894(CHEMBL197283 | N-(1-(3,4-dimethylbenzyl)piperidin-...)
Affinity DataIC50:  1.38E+3nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174901(5-chloro-N-(1-(naphthalen-2-ylmethyl)piperidin-4-y...)
Affinity DataIC50:  1.82E+3nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174905(5-chloro-N-(1-((2,3-dihydrobenzo[b][1,4]dioxin-6-y...)
Affinity DataIC50:  1.89E+3nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174902(CHEMBL383150 | N-(1-(benzo[d][1,3]dioxol-5-ylmethy...)
Affinity DataIC50: >2.00E+3nMAssay Description:Binding affinity to human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174899((3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-...)
Affinity DataIC50:  2.54E+3nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174910(3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)piperidin-4-y...)
Affinity DataIC50:  3.40E+3nMAssay Description:Functional antagonism of MCH-mediated calcium release by FLIPR using human MCHr1 from neuronal IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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