Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 1022
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8117(Hydroxyethylene Sulfone 17b | N-[(2S,3R,5S)-1-(3-b...)
Affinity DataKi:  45nM ΔG°:  -41.9kJ/mole IC50:  85nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8123(Hydroxyethylene Sulfone 18a | N-((1S,2R,4S)-1-(3-b...)
Affinity DataKi:  370nM ΔG°:  -36.7kJ/mole IC50:  530nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8124(Hydroxyethylene Sulfone 18b | N-((1S,2R,4S)-1-(3-b...)
Affinity DataKi:  540nM ΔG°:  -35.8kJ/mole IC50:  790nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8118(Hydroxyethylene Sulfone 17b- | N-[(2R,3S,5R)-1-(3-...)
Affinity DataKi:  1.40E+3nM ΔG°:  -33.4kJ/mole IC50:  2.00E+3nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8121((2R)-N-[(2S,3R,5S)-1-(3-bromophenyl)-7-(2,4-dichlo...)
Affinity DataKi:  2.90E+3nM ΔG°:  -31.6kJ/mole IC50:  4.20E+3nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8120(2-bromo-N-[(2S,3R,5S)-1-(3-bromophenyl)-7-(2,4-dic...)
Affinity DataKi:  3.10E+3nM ΔG°:  -31.4kJ/mole IC50:  4.50E+3nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8119(Hydroxyethylene Sulfone 17c | N-[(2S,3R,5S)-1-(3-b...)
Affinity DataKi:  7.00E+3nM ΔG°:  -29.4kJ/mole IC50:  1.00E+4nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8122((2R)-N-[(2R,3S,5R)-1-(3-bromophenyl)-7-(2,4-dichlo...)
Affinity DataKi: >4.00E+4nM ΔG°: >-25.1kJ/mole IC50: >4.00E+4nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Philipps-Universitat Marburg

LigandPNGBDBM8116(Hydroxyethylene Sulfone 17a | N-[(2S,3R,5S)-1-(3-b...)
Affinity DataKi: >4.00E+4nM ΔG°: >-25.1kJ/mole IC50: >4.00E+4nMpH: 5.5 T: 2°CAssay Description:The inhibition assays were performed by mixing enzyme and fluorogenic substrate in the presence of inhibitor compounds. The hydrolysis of the substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed