Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50016998
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176241BDBM50176241((S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-((E)-3...)
Affinity DataKi:  1nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176224BDBM50176224((S)-N-((E)-3-(1H-imidazol-5-yl)allyl)-1-((R)-2-ami...)
Affinity DataKi:  2nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133525BDBM50133525(N-(4-Amino-cyclohexylmethyl)-2-(6-methyl-2-oxo-3-p...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176237BDBM50176237((S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-(3-(4-...)
Affinity DataKi:  6nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176242BDBM50176242(N-(((trans)-4-aminocyclohexyl)methyl)-2-(6-methyl-...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176226BDBM50176226(N-((4-methyl-1H-imidazol-5-yl)methyl)-2-(6-methyl-...)
Affinity DataKi:  8nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176222BDBM50176222(N-((2-amino-4-methylthiazol-5-yl)methyl)-2-(6-meth...)
Affinity DataKi:  10nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50095198BDBM50095198((S)-1-((R)-2-Amino-3,3-diphenyl-propionyl)-pyrroli...)
Affinity DataKi:  13nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176239BDBM50176239((S)-N-(3-(1H-imidazol-5-yl)propyl)-1-((R)-2-amino-...)
Affinity DataKi:  17nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176236BDBM50176236(N-((4-methyl-1H-imidazol-5-yl)methyl)-2-(6-methyl-...)
Affinity DataKi:  22nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176225BDBM50176225((S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-((E)-3...)
Affinity DataKi:  30nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176240BDBM50176240(N-(3-(1H-imidazol-5-yl)propyl)-2-(6-methyl-2-oxo-3...)
Affinity DataKi:  34nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176238BDBM50176238(N-((4-methyl-1H-imidazol-5-yl)methyl)-2-(6-methyl-...)
Affinity DataKi:  53nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176233BDBM50176233((S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-((4-me...)
Affinity DataKi:  65nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176235BDBM50176235((E)-N-(3-(1H-imidazol-5-yl)allyl)-2-(6-methyl-2-ox...)
Affinity DataKi:  143nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176234BDBM50176234(N-((1H-imidazol-5-yl)methyl)-2-(6-methyl-2-oxo-3-(...)
Affinity DataKi:  170nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176221BDBM50176221((S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-(2-(2-...)
Affinity DataKi:  193nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176223BDBM50176223((S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-(3-(2-...)
Affinity DataKi:  198nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176230BDBM50176230((S)-N-(2-(1H-imidazol-5-yl)ethyl)-1-((R)-2-amino-3...)
Affinity DataKi:  200nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176231BDBM50176231((S)-1-((R)-2-amino-3,3-diphenylpropanoyl)-N-((2-am...)
Affinity DataKi:  350nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176228BDBM50176228((S)-N-((1H-imidazol-5-yl)methyl)-1-((R)-2-amino-3,...)
Affinity DataKi:  380nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176229BDBM50176229(N-(3-(2-aminothiazol-5-yl)propyl)-2-(6-methyl-2-ox...)
Affinity DataKi:  450nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176232BDBM50176232(N-((2-aminothiazol-5-yl)methyl)-2-(6-methyl-2-oxo-...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50176227BDBM50176227((E)-N-(3-(2-aminothiazol-5-yl)allyl)-2-(6-methyl-2...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity to thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed