Compile Data Set for Download or QSAR
maximum 50k data
Found 63 Enz. Inhib. hit(s) with all data for entry = 50017029
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176545(3-(difluoromethyl)-5-((2R,6S)-2,6-dimethylmorpholi...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against COX2 in feline whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176555(3-(difluoromethyl)-5-(3-methylpiperidin-1-yl)-1-(5...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176552(1-(5-(methylsulfonyl)pyridin-2-yl)-5-((tetrahydrof...)
Affinity DataIC50:  63nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176557(5-(3,5-dimethylpiperidin-1-yl)-1-(5-(methylsulfony...)
Affinity DataIC50:  95nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176534(5-(cyclopropylmethylamino)-1-(5-(methylsulfonyl)py...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176531(1-(5-methanesulfonyl-pyridin-2-yl)-5-(4-methyl-ben...)
Affinity DataIC50:  115nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176533(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(thiophen-2-y...)
Affinity DataIC50:  125nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176554(5-((1,3-dioxolan-2-yl)methylamino)-1-(5-(methylsul...)
Affinity DataIC50:  126nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176529(6-(4-cyano-5-(neopentylamino)-3-(trifluoromethyl)-...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176544(5-(azepan-1-yl)-3-(difluoromethyl)-1-(5-(methylsul...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176547(5-(3-methylbutan-2-ylamino)-1-(5-(methylsulfonyl)p...)
Affinity DataIC50:  132nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176542(5-((cis)-2,6-dimethylmorpholino)-1-(5-(methylsulfo...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176540(6-(5-(bicyclo[2.2.1]heptan-2-ylamino)-4-cyano-3-(t...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176536(5-(bicyclo[2.2.1]heptan-2-ylamino)-1-(5-(methylsul...)
Affinity DataIC50:  144nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176538(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(piperidin-1-...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176530(5-((1,3-dioxolan-2-yl)methylamino)-3-(difluorometh...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176541(6-(4-cyano-5-(2-methylbutylamino)-3-(trifluorometh...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176539(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(pentan-3-yla...)
Affinity DataIC50:  197nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176532(6-(4-cyano-3-(difluoromethyl)-5-(2-methylbutylamin...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176558(3-(difluoromethyl)-1-(5-(methylsulfonyl)pyridin-2-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176546(6-(4-cyano-3-(difluoromethyl)-5-((cis)-3,5-dimethy...)
Affinity DataIC50:  210nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176537(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(neopentylami...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176545(3-(difluoromethyl)-5-((2R,6S)-2,6-dimethylmorpholi...)
Affinity DataIC50:  240nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176556(5-(2-methylcyclohexylamino)-1-(5-(methylsulfonyl)p...)
Affinity DataIC50:  297nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50137425(2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...)
Affinity DataIC50:  310nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176535(5-(isopropylamino)-1-(5-(methylsulfonyl)pyridin-2-...)
Affinity DataIC50:  360nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176550(6-(4-cyano-3-(difluoromethyl)-5-(neopentylamino)-1...)
Affinity DataIC50:  360nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176548(5-(bicyclo[2.2.1]heptan-2-ylamino)-3-(difluorometh...)
Affinity DataIC50:  420nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176543(6-(4-cyano-5-((tetrahydrofuran-2-yl)methylamino)-3...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176553(6-(4-cyano-5-(3,5-dimethylpiperidin-1-yl)-3-(trifl...)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176555(3-(difluoromethyl)-5-(3-methylpiperidin-1-yl)-1-(5...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176547(5-(3-methylbutan-2-ylamino)-1-(5-(methylsulfonyl)p...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176532(6-(4-cyano-3-(difluoromethyl)-5-(2-methylbutylamin...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176541(6-(4-cyano-5-(2-methylbutylamino)-3-(trifluorometh...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176551(6-(4-cyano-3-(difluoromethyl)-5-((cis)-2,6-dimethy...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176533(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(thiophen-2-y...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176539(1-(5-(methylsulfonyl)pyridin-2-yl)-5-(pentan-3-yla...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176546(6-(4-cyano-3-(difluoromethyl)-5-((cis)-3,5-dimethy...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176549(6-(4-cyano-5-((cis)-2,6-dimethylmorpholino)-3-(tri...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176556(5-(2-methylcyclohexylamino)-1-(5-(methylsulfonyl)p...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176544(5-(azepan-1-yl)-3-(difluoromethyl)-1-(5-(methylsul...)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176529(6-(4-cyano-5-(neopentylamino)-3-(trifluoromethyl)-...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176543(6-(4-cyano-5-((tetrahydrofuran-2-yl)methylamino)-3...)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176540(6-(5-(bicyclo[2.2.1]heptan-2-ylamino)-4-cyano-3-(t...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176536(5-(bicyclo[2.2.1]heptan-2-ylamino)-1-(5-(methylsul...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176552(1-(5-(methylsulfonyl)pyridin-2-yl)-5-((tetrahydrof...)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176550(6-(4-cyano-3-(difluoromethyl)-5-(neopentylamino)-1...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176548(5-(bicyclo[2.2.1]heptan-2-ylamino)-3-(difluorometh...)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176531(1-(5-methanesulfonyl-pyridin-2-yl)-5-(4-methyl-ben...)
Affinity DataIC50:  2.15E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Veterinary Medicine Research And Development Pfizer

Curated by ChEMBL
LigandPNGBDBM50176534(5-(cyclopropylmethylamino)-1-(5-(methylsulfonyl)py...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 63 total ) | Next | Last >>
Jump to: