Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with all data for entry = 50017065
TargetTrypanothione reductase(Trypanosoma cruzi)
Biochemie-Zentrum Der UniversitäT Heidelberg

Curated by ChEMBL
LigandPNGBDBM50177103(1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase after 5 mins preincubation with NADPH in presence of 100 uM TS2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Biochemie-Zentrum Der UniversitäT Heidelberg

Curated by ChEMBL
LigandPNGBDBM50177103(1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human glutathione reductase after 5 mins preincubation with NADPH in presence of 500 uM GSSG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Biochemie-Zentrum Der UniversitäT Heidelberg

Curated by ChEMBL
LigandPNGBDBM50177103(1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase in presence of 100 uM TS2 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Biochemie-Zentrum Der UniversitäT Heidelberg

Curated by ChEMBL
LigandPNGBDBM50177103(1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of human glutathione reductase in presence of 50 uM GSSG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Biochemie-Zentrum Der UniversitäT Heidelberg

Curated by ChEMBL
LigandPNGBDBM50177103(1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...)
Affinity DataIC50:  1.90E+5nMAssay Description:Inhibition of human glutathione reductase in presence of 500 uM GSSG substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed