Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50037862
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095261((3-Chloro-phenyl)-(6,7-diethoxy-quinazolin-4-yl)-a...)
Affinity DataIC50:  0.380nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3556(4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline |...)
Affinity DataIC50:  0.410nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095273((6,7-Diethoxy-quinazolin-4-yl)-(3-iodo-phenyl)-ami...)
Affinity DataIC50:  0.640nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  0.660nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3533(CHEMBL1204305 | CHEMBL96065 | N-(3-iodophenyl)-6,7...)
Affinity DataIC50:  1.05nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095261((3-Chloro-phenyl)-(6,7-diethoxy-quinazolin-4-yl)-a...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3532(CHEMBL540068 | CHEMBL7917 | N-(3-chlorophenyl)-6,7...)
Affinity DataIC50:  1.26nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3556(4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline |...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095273((6,7-Diethoxy-quinazolin-4-yl)-(3-iodo-phenyl)-ami...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3531(CHEMBL541586 | CHEMBL94431 | N-(3-fluorophenyl)-6,...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3533(CHEMBL1204305 | CHEMBL96065 | N-(3-iodophenyl)-6,7...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095277((6,7-Diethoxy-quinazolin-4-yl)-(3-fluoro-phenyl)-a...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370935(CHEMBL1203937)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095277((6,7-Diethoxy-quinazolin-4-yl)-(3-fluoro-phenyl)-a...)
Affinity DataIC50:  8.17nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370943(CHEMBL1203935)
Affinity DataIC50:  8.95nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370938(CHEMBL1203939)
Affinity DataIC50:  9.31nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50177114(CHEMBL1203938 | CHEMBL374810 | cid_1474879)
Affinity DataIC50:  10.9nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM4619(Anilinoquinazoline deriv. 2 | CHEMBL1204360 | CHEM...)
Affinity DataIC50:  12.8nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370938(CHEMBL1203939)
Affinity DataIC50:  15.8nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370934(CHEMBL1203940)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370935(CHEMBL1203937)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370942(CHEMBL1203936)
Affinity DataIC50:  19.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370944(CHEMBL1203934)
Affinity DataIC50:  19.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370942(CHEMBL1203936)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370934(CHEMBL1203940)
Affinity DataIC50:  23.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3531(CHEMBL541586 | CHEMBL94431 | N-(3-fluorophenyl)-6,...)
Affinity DataIC50:  31.9nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM4619(Anilinoquinazoline deriv. 2 | CHEMBL1204360 | CHEM...)
Affinity DataIC50:  32.2nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50177114(CHEMBL1203938 | CHEMBL374810 | cid_1474879)
Affinity DataIC50:  47.7nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370943(CHEMBL1203935)
Affinity DataIC50: >50nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3556(4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline |...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370944(CHEMBL1203934)
Affinity DataIC50:  51nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095273((6,7-Diethoxy-quinazolin-4-yl)-(3-iodo-phenyl)-ami...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50095273((6,7-Diethoxy-quinazolin-4-yl)-(3-iodo-phenyl)-ami...)
Affinity DataIC50:  69nMAssay Description:Inhibition of human ErbB2 tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370935(CHEMBL1203937)
Affinity DataIC50: >100nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3032(CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...)
Affinity DataIC50:  143nMAssay Description:Inhibition of human ErbB2 tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM3556(4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline |...)
Affinity DataIC50:  215nMAssay Description:Inhibition of human ErbB2 tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

Curated by ChEMBL
LigandPNGBDBM50370935(CHEMBL1203937)
Affinity DataIC50:  231nMAssay Description:Inhibition of human ErbB2 tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed