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Found 17 Enz. Inhib. hit(s) with all data for entry = 50017103
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM27498(10-amino-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177482(1,2,3,11-Tetrahydro-5,11-diaza-benzo[a]trindene-4,...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177478(1,7,8,9-tetrahydro-1,5-diaza-trindene-4,6-dione | ...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177476(1,2,3,5,6,11-hexahydro-5,11-diaza-benzo[a]trinden-...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177486(4,5-dimethylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dio...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177472(CHEMBL373066 | pyrrolo[3,4-e]indole-1,3(2H,6H)-dio...)
Affinity DataIC50:  750nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177481(4-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione |...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177480(7,8-dihydrocyclopenta[e]isoindole-1,3(2H,6H)-dione...)
Affinity DataIC50:  2.22E+3nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177483(5-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione |...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177485(2,3-dihydro-1H-11-thia-5-aza-benzo[a]trindene-4,6-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177484(4,14-diazapentacyclo[11.7.0.0^{2,6}.0^{7,12}.0^{15...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177479(1,2,3,4,5,11-hexahydro-5,11-diaza-benzo[a]trinden-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50134580(1,2,3,8-tetrahydro-benzo[a]pyrrolo[3,4-c]carbazole...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177477(CHEMBL370869 | pyrrolo[3,4-c]carbazole-1,3(2H,6H)-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177475(5-ethyl-4-propylpyrrolo[3,4-c]carbazole-1,3(2H,6H)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177474(1,2-dihydro-11H-3-oxa-5,11-diaza-benzo[a]trindene-...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177473(2,3-dihydro-1H-11-oxa-5-aza-benzo[a]trindene-4,6-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed