Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50017103
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM27498(4-Amino-1,8-naphthalimide | 10-amino-3-azatricyclo...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177482(4,5,6,7-tetrahydro-1Hcyclopenta[a]pyrrolo[3,4-c]ca...)
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177478(1,7,8,9-tetrahydro-1,5-diaza-trindene-4,6-dione | ...)
Affinity DataIC50: 40nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177476(1,2,3,5,6,11-hexahydro-5,11-diaza-benzo[a]trinden-...)
Affinity DataIC50: 90nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177486(4,5-dimethylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dio...)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177472(pyrrolo[3,4-e]indole-1,3(2H,6H)-dione | CHEMBL3730...)
Affinity DataIC50: 750nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177481(4-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione |...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177480(7,8-dihydrocyclopenta[e]isoindole-1,3(2H,6H)-dione...)
Affinity DataIC50: 2.22E+3nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177483(5-methylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione |...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177485(2,3-dihydro-1H-11-thia-5-aza-benzo[a]trindene-4,6-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177484(4,14-diazapentacyclo[11.7.0.0^{2,6}.0^{7,12}.0^{15...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177479(1,2,3,4,5,11-hexahydro-5,11-diaza-benzo[a]trinden-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50134580(1,2,3,8-tetrahydro-benzo[a]pyrrolo[3,4-c]carbazole...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177477(pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione | CHEMBL3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177475(5-ethyl-4-propylpyrrolo[3,4-c]carbazole-1,3(2H,6H)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177474(1,2-dihydro-11H-3-oxa-5,11-diaza-benzo[a]trindene-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50177473(2,3-dihydro-1H-11-oxa-5-aza-benzo[a]trindene-4,6-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed