Compile Data Set for Download or QSAR
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Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50017114
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177643((R)-[8-chloro-6-(1-piperazinyl)-1H-benzo[5,6]]cycl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of farnesyltransferase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177643((R)-[8-chloro-6-(1-piperazinyl)-1H-benzo[5,6]]cycl...)
Affinity DataIC50:  72nMAssay Description:Inhibition of farnesyltransferase activity in COS7 cells transfected with Ras gene in soft agar proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177642((R)-8-chloro-11-(1-methanesulfonyl-piperidin-4-yl)...)
Affinity DataIC50:  76nMAssay Description:Inhibition of farnesyltransferase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDimer of Protein farnesyltransferase subunit beta(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177641((S)-8-chloro-11-(1-methanesulfonyl-piperidin-4-yl)...)
Affinity DataIC50:  150nMAssay Description:Inhibition of farnesyltransferase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed