Compile Data Set for Download or QSAR
maximum 50k data
Found 58 Enz. Inhib. hit(s) with all data for entry = 50017175
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178593(2-(5-fluoro-1H-indol-3-yl)-N-((4-isopropyl-3,4-dih...)
Affinity DataKi:  2.81nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178598(2-(5-fluoro-1H-indol-3-yl)-N-((8-methoxy-3,4-dihyd...)
Affinity DataKi:  3.13nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178596(2-(1H-indol-3-yl)-N-((4-methyl-3,4-dihydro-2H-benz...)
Affinity DataKi:  5.86nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178602(CHEMBL380342 | N-((3,4-dihydro-2H-benzo[b][1,4]oxa...)
Affinity DataKi:  6.91nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178589(2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-...)
Affinity DataKi:  6.94nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178607(2-(5-fluoro-1H-indol-3-yl)-N-((4-phenyl-3,4-dihydr...)
Affinity DataKi:  7.14nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178608(CHEMBL380655 | N-((4-benzyl-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  7.25nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178594(2-(5-fluoro-1H-indol-3-yl)-N-((4-isobutyl-3,4-dihy...)
Affinity DataKi:  8.15nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178600(2-((4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)...)
Affinity DataKi:  8.37nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178588(2-(5-fluoro-1H-indol-3-yl)-N-((4-methyl-3,4-dihydr...)
Affinity DataKi:  8.46nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178598(2-(5-fluoro-1H-indol-3-yl)-N-((8-methoxy-3,4-dihyd...)
Affinity DataKi:  9.31nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178592(CHEMBL410273 | N-((3,4-dihydro-2H-benzo[b][1,4]oxa...)
Affinity DataKi:  11.0nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178590(2-(5-fluoro-1H-indol-3-yl)-N-((7-methoxy-3,4-dihyd...)
Affinity DataKi:  11.7nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178588(2-(5-fluoro-1H-indol-3-yl)-N-((4-methyl-3,4-dihydr...)
Affinity DataKi:  12.4nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178591(2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-...)
Affinity DataKi:  12.6nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178597(2-(1H-indol-3-yl)-N-((4-propyl-3,4-dihydro-2H-benz...)
Affinity DataKi:  12.8nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178601(4-ethyl-2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydro...)
Affinity DataKi:  13.2nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178587(CHEMBL206644 | N-((4-ethyl-3,4-dihydro-2H-benzo[b]...)
Affinity DataKi:  15.3nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178587(CHEMBL206644 | N-((4-ethyl-3,4-dihydro-2H-benzo[b]...)
Affinity DataKi:  15.3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178592(CHEMBL410273 | N-((3,4-dihydro-2H-benzo[b][1,4]oxa...)
Affinity DataKi:  16.0nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178593(2-(5-fluoro-1H-indol-3-yl)-N-((4-isopropyl-3,4-dih...)
Affinity DataKi:  21.1nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178595(2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-...)
Affinity DataKi:  22.6nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178597(2-(1H-indol-3-yl)-N-((4-propyl-3,4-dihydro-2H-benz...)
Affinity DataKi:  22.7nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178606(3-(1H-indol-3-yl)-N-((4-isopropyl-3,4-dihydro-2H-b...)
Affinity DataKi:  23.8nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178603(2-(1H-indol-3-yl)-N-((4-phenyl-3,4-dihydro-2H-benz...)
Affinity DataKi:  30.2nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178605(CHEMBL382857 | N-((7-chloro-4-methyl-3,4-dihydro-2...)
Affinity DataKi:  42.6nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178594(2-(5-fluoro-1H-indol-3-yl)-N-((4-isobutyl-3,4-dihy...)
Affinity DataKi:  51.5nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178605(CHEMBL382857 | N-((7-chloro-4-methyl-3,4-dihydro-2...)
Affinity DataKi:  75.2nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178604(3-(1H-indol-3-yl)-N-((4-phenyl-3,4-dihydro-2H-benz...)
Affinity DataKi:  75.8nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178599(CHEMBL381542 | N-((4-benzyl-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  76.1nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178596(2-(1H-indol-3-yl)-N-((4-methyl-3,4-dihydro-2H-benz...)
Affinity DataKi:  88.5nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178602(CHEMBL380342 | N-((3,4-dihydro-2H-benzo[b][1,4]oxa...)
Affinity DataKi:  89.8nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178606(3-(1H-indol-3-yl)-N-((4-isopropyl-3,4-dihydro-2H-b...)
Affinity DataKi:  90.4nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178590(2-(5-fluoro-1H-indol-3-yl)-N-((7-methoxy-3,4-dihyd...)
Affinity DataKi:  103nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178599(CHEMBL381542 | N-((4-benzyl-3,4-dihydro-2H-benzo[b...)
Affinity DataKi:  109nMAssay Description:Displacement of [3H]paroxetine from rat cortical 5-HT reuptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178601(4-ethyl-2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydro...)
Affinity DataKi:  136nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178591(2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178589(2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-...)
Affinity DataKi:  155nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178595(2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-...)
Affinity DataKi:  363nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178600(2-((4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)...)
Affinity DataKi:  805nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178596(2-(1H-indol-3-yl)-N-((4-methyl-3,4-dihydro-2H-benz...)
Affinity DataEC50:  33.6nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178591(2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-...)
Affinity DataEC50:  190nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178587(CHEMBL206644 | N-((4-ethyl-3,4-dihydro-2H-benzo[b]...)
Affinity DataEC50:  90nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178595(2-((4-(5-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-...)
Affinity DataEC50:  135nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178590(2-(5-fluoro-1H-indol-3-yl)-N-((7-methoxy-3,4-dihyd...)
Affinity DataEC50:  182nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178594(2-(5-fluoro-1H-indol-3-yl)-N-((4-isobutyl-3,4-dihy...)
Affinity DataEC50:  329nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178598(2-(5-fluoro-1H-indol-3-yl)-N-((8-methoxy-3,4-dihyd...)
Affinity DataEC50:  52.2nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178600(2-((4-(1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)...)
Affinity DataEC50:  1.13E+3nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178599(CHEMBL381542 | N-((4-benzyl-3,4-dihydro-2H-benzo[b...)
Affinity DataEC50:  1.39E+3nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50178593(2-(5-fluoro-1H-indol-3-yl)-N-((4-isopropyl-3,4-dih...)
Affinity DataEC50:  191nMAssay Description:Intrinsic activity assessed by stimulation of [35S]GTPgammaS binding in CHO cells expressing 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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