Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50017191
TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50:  3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50:  3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178843((3R)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178830(CHEMBL205078 | N-(4-(2-(4-fluorophenylamino)pyridi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178832(CHEMBL203535 | N-(2'-(phenylamino)-4,4'-bipyridin-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178836(CHEMBL203059 | N-(4-(2-(phenylamino)pyridin-4-yl)p...)
Affinity DataIC50:  8nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178846(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50:  9nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178842((3S)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50:  10nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178839(CHEMBL202676 | cis-N-(4-(2-(4-fluorophenylamino)py...)
Affinity DataIC50:  15nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178838(1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178848(CHEMBL205672 | N-(4-fluorophenyl)-4-(2-(4-fluoroph...)
Affinity DataIC50:  17nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178837(CHEMBL380724 | N-(4-(2-(phenylamino)pyridin-4-yl)p...)
Affinity DataIC50:  18nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178829(3-methoxy-N-(4-(2-(phenylamino)pyridin-4-yl)pyridi...)
Affinity DataIC50:  20nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178841(4-methoxy-N-(4-(2-(phenylamino)pyridin-4-yl)pyridi...)
Affinity DataIC50:  32nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178840(CHEMBL203289 | N-(2-fluorophenyl)-4-(2-(2-fluoroph...)
Affinity DataIC50:  32nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178844(5-methyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50:  33nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178846(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50:  37nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178839(CHEMBL202676 | cis-N-(4-(2-(4-fluorophenylamino)py...)
Affinity DataIC50:  40nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178837(CHEMBL380724 | N-(4-(2-(phenylamino)pyridin-4-yl)p...)
Affinity DataIC50:  42nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178825(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50:  44nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50:  48nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50:  48nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178843((3R)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50:  50nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178843((3R)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50:  74nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178846(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50:  82nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178838(1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl...)
Affinity DataIC50:  85nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178839(CHEMBL202676 | cis-N-(4-(2-(4-fluorophenylamino)py...)
Affinity DataIC50:  88nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178841(4-methoxy-N-(4-(2-(phenylamino)pyridin-4-yl)pyridi...)
Affinity DataIC50:  106nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178834(CHEMBL203792 | N1-(4-(2-(2-aminophenylamino)pyridi...)
Affinity DataIC50:  108nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178836(CHEMBL203059 | N-(4-(2-(phenylamino)pyridin-4-yl)p...)
Affinity DataIC50:  122nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178842((3S)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50:  125nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178830(CHEMBL205078 | N-(4-(2-(4-fluorophenylamino)pyridi...)
Affinity DataIC50:  152nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178842((3S)-1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin...)
Affinity DataIC50:  162nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178838(1-acetyl-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl...)
Affinity DataIC50:  171nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178828(CHEMBL380625 | N-(4-(2-(phenylamino)pyridin-4-yl)p...)
Affinity DataIC50:  175nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178832(CHEMBL203535 | N-(2'-(phenylamino)-4,4'-bipyridin-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178830(CHEMBL205078 | N-(4-(2-(4-fluorophenylamino)pyridi...)
Affinity DataIC50:  199nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178849(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50:  207nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178825(1-acetyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50:  219nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178847(CHEMBL203631 | N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-...)
Affinity DataIC50:  235nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178836(CHEMBL203059 | N-(4-(2-(phenylamino)pyridin-4-yl)p...)
Affinity DataIC50:  251nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178844(5-methyl-N-(4-(2-(phenylamino)pyridin-4-yl)pyridin...)
Affinity DataIC50:  261nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178832(CHEMBL203535 | N-(2'-(phenylamino)-4,4'-bipyridin-...)
Affinity DataIC50:  384nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178829(3-methoxy-N-(4-(2-(phenylamino)pyridin-4-yl)pyridi...)
Affinity DataIC50:  451nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178826(CHEMBL437706 | N-(2-methoxyphenyl)-4-(2-(2-methoxy...)
Affinity DataIC50:  528nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50:  581nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178827((+)-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyri...)
Affinity DataIC50:  581nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178831(4-(2-(o-toluidino)pyridin-4-yl)-N-o-tolylpyridin-2...)
Affinity DataIC50:  652nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178835(CHEMBL202961 | N-(2-ethoxyphenyl)-4-(2-(2-ethoxyph...)
Affinity DataIC50:  693nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 8(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50178828(CHEMBL380625 | N-(4-(2-(phenylamino)pyridin-4-yl)p...)
Affinity DataIC50:  780nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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