Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 2253
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18656BDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataKi:  4.60nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18656BDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataKi:  6.20nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18525BDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataKi:  14nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18525BDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataKi:  19nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18656BDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 110nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18636BDBM18636((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 120nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18645BDBM18645((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 130nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18637BDBM18637((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 140nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18649BDBM18649((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(6...)
Affinity DataIC50: 170nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18646BDBM18646((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2...)
Affinity DataIC50: 190nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18634BDBM18634((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2...)
Affinity DataIC50: 200nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18654BDBM18654((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(6...)
Affinity DataIC50: 200nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18655BDBM18655(4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-dimethyl...)
Affinity DataIC50: 210nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18650BDBM18650((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 220nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18644BDBM18644((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 250nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18643BDBM18643((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 330nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18659BDBM18659((2R,5S)-N-(6-aminopyridin-3-yl)-4-[4-cyano-3-(trif...)
Affinity DataIC50: 370nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18648BDBM18648((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(5...)
Affinity DataIC50: 440nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18652BDBM18652(methyl 5-{[(2R,5S)-4-[4-cyano-3-(trifluoromethyl)p...)
Affinity DataIC50: 470nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18653BDBM18653((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(6...)
Affinity DataIC50: 500nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18642BDBM18642((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 680nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18651BDBM18651((2R,5S)-N-(6-chloropyridin-3-yl)-4-[4-cyano-3-(tri...)
Affinity DataIC50: 730nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18525BDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataIC50: 890nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18640BDBM18640((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 1.00E+3nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18647BDBM18647((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(4...)
Affinity DataIC50: 1.20E+3nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18657BDBM18657((2S,5R)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 1.30E+3nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Rat)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18656BDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataKi:  3.30E+3nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18639BDBM18639((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 4.60E+3nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Rat)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18525BDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataKi:  7.20E+3nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18635BDBM18635((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 7.80E+3nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18638BDBM18638((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 1.00E+4nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18641BDBM18641(3-{[(2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-...)
Affinity DataIC50: 1.00E+4nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandChemical structure of BindingDB Monomer ID 18658BDBM18658((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(6...)
Affinity DataIC50: 1.00E+4nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed