Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 2253
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataKi:  4.60nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Astellas Pharma

LigandPNGBDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataKi:  6.20nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
Astellas Pharma

LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataKi:  14nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataKi:  19nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 110nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18636((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 120nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18645((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 130nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18637((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 140nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18649((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(6...)
Affinity DataIC50: 170nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18646((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2...)
Affinity DataIC50: 190nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18634((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2...)
Affinity DataIC50: 200nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18654((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(6...)
Affinity DataIC50: 200nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18655(4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-dimethyl...)
Affinity DataIC50: 210nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18650((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 220nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18644((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 250nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18643((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 330nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18659((2R,5S)-N-(6-aminopyridin-3-yl)-4-[4-cyano-3-(trif...)
Affinity DataIC50: 370nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18648((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(5...)
Affinity DataIC50: 440nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18652(methyl 5-{[(2R,5S)-4-[4-cyano-3-(trifluoromethyl)p...)
Affinity DataIC50: 470nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18653((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(6...)
Affinity DataIC50: 500nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18642((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 680nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18651((2R,5S)-N-(6-chloropyridin-3-yl)-4-[4-cyano-3-(tri...)
Affinity DataIC50: 730nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataIC50: 890nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18640((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 1.00E+3nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18647((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(4...)
Affinity DataIC50: 1.20E+3nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18657((2S,5R)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 1.30E+3nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Rat)
Astellas Pharma

LigandPNGBDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataKi:  3.30E+3nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18639((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 4.60E+3nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetProgesterone receptor(Rat)
Astellas Pharma

LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataKi:  7.20E+3nMAssay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18635((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 7.80E+3nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18638((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataIC50: 1.00E+4nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18641(3-{[(2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-...)
Affinity DataIC50: 1.00E+4nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Astellas Pharma

LigandPNGBDBM18658((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-N-(6...)
Affinity DataIC50: 1.00E+4nMpH: 7.8Assay Description:Activities of the test compounds to inhibit androgen receptor mediated transcription induced by DHT were evaluated using stable transfected AR/CHO#3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2007
Entry Details Article
PubMed