Compile Data Set for Download or QSAR
maximum 50k data
Found 13 Enz. Inhib. hit(s) with all data for entry = 50017420
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181954((S)-5-tert-butyl-1-(3,3-dimethyl-butyl)-3-(1,1-dio...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181957((S)-5-tert-butyl-3-(1,1-dioxo-1,4-dihydro-1-benzo[...)
Affinity DataIC50:  18nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181956((S)-1-benzyl-5-tert-butyl-3-(1,1-dioxo-1,4-dihydro...)
Affinity DataIC50:  22nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181955((S)-5-tert-butyl-3-(1,1-dioxo-1,4-dihydro-1-benzo[...)
Affinity DataIC50:  59nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181958((S)-1-benzyl-5-sec-butyl-3-(1,1-dioxo-1,4-dihydro-...)
Affinity DataIC50:  88nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181964((S)-3-(1,1-dioxo-1,4-dihydro-1-benzo[1,2,4]thiadia...)
Affinity DataIC50:  147nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM30406(CHEMBL176058 | benzo[1,2,4]thiadiazine-1,1-dioxide...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181961((S)-5-cyclohexyl-1-(3,3-dimethyl-butyl)-3-(1,1-dio...)
Affinity DataIC50:  486nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181962((S)-5-tert-butyl-1-(2-cyclopropyl-ethyl)-3-(1,1-di...)
Affinity DataIC50:  530nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181960((S)-1-(3,3-dimethyl-butyl)-3-(1,1-dioxo-1,4-dihydr...)
Affinity DataIC50: >748nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181965((S)-3-(1,1-dioxo-1,4-dihydro-1-benzo[1,2,4]thiadia...)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181959((S)-5-benzyl-3-(1,1-dioxo-1,4-dihydro-1-benzo[1,2,...)
Affinity DataIC50:  3.57E+3nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181963((S)-5-tert-butyl-3-(1,1-dioxo-1,4-dihydro-1-benzo[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HCV NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed