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Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50034614
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365216(CHEMBL1956070 | ROCHE screening, 76)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human GST-tagged CDK4-cyclin D1 using his-tagged Rb as substrate after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365217(CHEMBL1956069)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human GST-tagged CDK4-cyclin D1 using his-tagged Rb as substrate after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365217(CHEMBL1956069)
Affinity DataIC50:  1.97E+6nMAssay Description:Inhibition of human CDK1-GST-tagged cyclin B using his-tagged Rb as substrate after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365216(CHEMBL1956070 | ROCHE screening, 76)
Affinity DataIC50:  2.36E+6nMAssay Description:Inhibition of human CDK2-GST-tagged cyclin E using his-tagged Rb as substrate after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365216(CHEMBL1956070 | ROCHE screening, 76)
Affinity DataIC50:  3.04E+6nMAssay Description:Inhibition of human CDK1-GST-tagged cyclin B using his-tagged Rb as substrate after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365216(CHEMBL1956070 | ROCHE screening, 76)
Affinity DataIC50:  3.21E+6nMAssay Description:Inhibition of Src using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365217(CHEMBL1956069)
Affinity DataIC50:  3.48E+6nMAssay Description:Inhibition of Src using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365217(CHEMBL1956069)
Affinity DataIC50:  4.14E+6nMAssay Description:Inhibition of human CDK2-GST-tagged cyclin E using his-tagged Rb as substrate after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365216(CHEMBL1956070 | ROCHE screening, 76)
Affinity DataIC50: >2.00E+7nMAssay Description:Inhibition of c-Met using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365217(CHEMBL1956069)
Affinity DataIC50: >2.00E+7nMAssay Description:Inhibition of c-Met using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor 1 receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365217(CHEMBL1956069)
Affinity DataIC50:  2.00E+7nMAssay Description:Inhibition of IGF1R using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor 1 receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365216(CHEMBL1956070 | ROCHE screening, 76)
Affinity DataIC50:  2.20E+7nMAssay Description:Inhibition of IGF1R using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365217(CHEMBL1956069)
Affinity DataIC50:  2.40E+7nMAssay Description:Inhibition of insulin receptor using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365216(CHEMBL1956070 | ROCHE screening, 76)
Affinity DataIC50:  7.10E+7nMAssay Description:Inhibition of insulin receptor using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365216(CHEMBL1956070 | ROCHE screening, 76)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of Lck using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365217(CHEMBL1956069)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of Lck using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 3(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365216(CHEMBL1956070 | ROCHE screening, 76)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of ERK1 using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 3(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50365217(CHEMBL1956069)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of ERK1 using fluorescent substrate by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed