Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50000536
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006990BDBM50006990(CHEMBL299499 | N-Adamantan-1-yl-N'-(4-iodo-phenyl)...)
Affinity DataIC50: 2.80nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006986BDBM50006986(CHEMBL442356 | N-Adamantan-1-yl-N'-(4-fluoro-2-met...)
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21398BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006991BDBM50006991(CHEMBL55970 | N-Adamantan-1-yl-N'-(2-iodo-phenyl)-...)
Affinity DataIC50: 6.20nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006983BDBM50006983(CHEMBL55873 | N-Adamantan-1-yl-N'-(4-methoxy-2-met...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006988BDBM50006988(CHEMBL54407 | N-Adamantan-1-yl-N'-(3-methoxy-pheny...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006987BDBM50006987(CHEMBL55769 | N-Adamantan-1-yl-N'-(3-iodo-phenyl)-...)
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006993BDBM50006993(CHEMBL293059 | N-Adamantan-1-yl-N'-(2-fluoro-pheny...)
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006989BDBM50006989(CHEMBL292450 | N-Adamantan-1-yl-N'-(4-fluoro-pheny...)
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006992BDBM50006992(CHEMBL292668 | N-Adamantan-1-yl-N'-(4-methoxy-phen...)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006984BDBM50006984(CHEMBL413257 | N-Adamantan-1-yl-N'-(3-fluoro-pheny...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006985BDBM50006985(CHEMBL301623 | N-Adamantan-1-yl-N'-(2-methoxy-phen...)
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81982BDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Institutions

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 81924BDBM81924(CAS_85976-54-1 | (R)-3-(1-Propyl-piperidin-3-yl)-p...)
Affinity DataIC50: 76nMAssay Description:Displacement of [3H]DTG from sigma opioid receptor of homogenized guinea pig whole brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed