Compile Data Set for Download or QSAR
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Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 2129
TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17223((2S)-2-{[(3S)-2-(benzenesulfonyl)-2-azabicyclo[2.2...)
Affinity DataIC50:  12nMpH: 7.4 T: 23°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17224((2S)-2-{[(3S)-2-(benzenesulfonyl)-2-azabicyclo[2.2...)
Affinity DataIC50:  26nMpH: 7.4 T: 23°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17222((2S)-2-{[(3S)-2-(benzenesulfonyl)-2-azabicyclo[2.2...)
Affinity DataIC50:  36nMpH: 7.4 T: 23°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-4/beta-1 [T112H](Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17225((2S)-2-{[(3S)-2-(benzenesulfonyl)-2-azabicyclo[2.2...)
Affinity DataIC50:  39nMpH: 7.4 T: 23°CAssay Description: Immulon 96-well plates were coated with recombinant hVCAM-1 overnight at 4 C. Plates were washed and blocked for 1 h at room temperature in PBS-BSA....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17223((2S)-2-{[(3S)-2-(benzenesulfonyl)-2-azabicyclo[2.2...)
Affinity DataIC50:  46nMpH: 7.4 T: 23°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17224((2S)-2-{[(3S)-2-(benzenesulfonyl)-2-azabicyclo[2.2...)
Affinity DataIC50:  110nMpH: 7.4 T: 23°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17222((2S)-2-{[(3S)-2-(benzenesulfonyl)-2-azabicyclo[2.2...)
Affinity DataIC50:  120nMpH: 7.4 T: 23°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetIntegrin alpha-4/beta-7(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM17225((2S)-2-{[(3S)-2-(benzenesulfonyl)-2-azabicyclo[2.2...)
Affinity DataIC50:  440nMpH: 7.4 T: 23°CAssay Description:M2 anti-FLAG antibody coated 96-well plates were coated with recombinant FLAG-hMAdCAM-1 contained in Dulbecco PBS. The compounds to be tested were ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed