Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50037697
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114263BDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 0.980nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182201BDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183865BDBM50183865(((R)-2-{(S)-2-[(4-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183877BDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182194BDBM50182194(CHEMBL206418 | {(R)-2-[(S)-2-(4-carbamimidoyl-benz...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183868BDBM50183868(((R)-2-{(S)-2-[(5-carbamimidoyl-4-methyl-thiophen-...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183870BDBM50183870(((R)-2-{(S)-2-[(4-carbamimidoyl-3-chloro-thiophen-...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183879BDBM50183879(((R)-2-{(S)-2-[(4-carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183872BDBM50183872(((R)-2-{(S)-2-[(5-carbamimidoyl-4-chloro-thiophen-...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129034BDBM50129034(CHEMBL207129 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-1H-...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183880BDBM50183880(((R)-2-{(S)-2-[(5-carbamimidoyl-thiophen-3-ylmethy...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183878BDBM50183878(((R)-2-{(S)-2-[(4-carbamimidoyl-3-methyl-thiophen-...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50129033BDBM50129033(CHEMBL207128 | CHEMBL543817 | ((R)-2-{(S)-2-[(5-Ca...)
Affinity DataIC50: 11nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183875BDBM50183875(((R)-2-{(S)-2-[(4-carbamimidoyl-oxazol-2-ylmethyl)...)
Affinity DataIC50: 21nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183887BDBM50183887(((R)-2-{(S)-2-[(3-carbamimidoyl-isoxazol-5-ylmethy...)
Affinity DataIC50: 34nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183888BDBM50183888(((R)-2-{(S)-2-[(2-carbamimidoyl-thiazol-4-ylmethyl...)
Affinity DataIC50: 44nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183866BDBM50183866(((R)-2-{(S)-2-[(5-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50: 49nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183876BDBM50183876(((R)-2-{(S)-2-[(5-carbamimidoyl-pyridin-2-ylmethyl...)
Affinity DataIC50: 51nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183869BDBM50183869(((R)-2-{(S)-2-[(5-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50: 51nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183890BDBM50183890(((R)-2-{(S)-2-[(5-amino-4-carbamimidoyl-thiophen-2...)
Affinity DataIC50: 57nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29388BDBM29388(Exanta | Melagatran | US11584714, Compound 999 | U...)
Affinity DataIC50: 69nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114263BDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 70nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183865BDBM50183865(((R)-2-{(S)-2-[(4-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50: 125nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183877BDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50: 173nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183877BDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50: 201nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183886BDBM50183886(((R)-2-{(S)-2-[(5-carbamimidoyl-2-methyl-2H-[1,2,4...)
Affinity DataIC50: 232nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183865BDBM50183865(((R)-2-{(S)-2-[(4-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50: 251nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114263BDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 328nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182201BDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 540nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183884BDBM50183884(((R)-2-{(S)-2-[(5-carbamimidoyl-[1,3,4]thiadiazol-...)
Affinity DataIC50: 566nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183868BDBM50183868(((R)-2-{(S)-2-[(5-carbamimidoyl-4-methyl-thiophen-...)
Affinity DataIC50: 687nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183877BDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50: 995nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183873BDBM50183873(((R)-2-{(S)-2-[(5-carbamimidoyl-1-methyl-1H-pyrazo...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183874BDBM50183874(((R)-2-{(S)-2-[(5-carbamimidoyl-3,4-dimethyl-thiop...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114263BDBM50114263(CHEMBL208140 | ((R)-2-{(S)-2-[(5-Carbamimidoyl-thi...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183889BDBM50183889(((R)-2-{(S)-2-[(3-carbamimidoyl-[1,2,4]oxadiazol-5...)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182201BDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183881BDBM50183881(((R)-2-{(S)-2-[(3-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183865BDBM50183865(((R)-2-{(S)-2-[(4-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183871BDBM50183871(((R)-2-{(S)-2-[(4-carbamimidoyl-5-methyl-thiazol-2...)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29388BDBM29388(Exanta | Melagatran | US11584714, Compound 999 | U...)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182201BDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29388BDBM29388(Exanta | Melagatran | US11584714, Compound 999 | U...)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183868BDBM50183868(((R)-2-{(S)-2-[(5-carbamimidoyl-4-methyl-thiophen-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Abbott

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183868BDBM50183868(((R)-2-{(S)-2-[(5-carbamimidoyl-4-methyl-thiophen-...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of F10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed