Compile Data Set for Download or QSAR
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Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50017569
TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50228760((S)-2-((R)-2-(3-chlorophenyl)-2-hydroxyacetamido)-...)
Affinity DataIC50:  116nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50228761((S)-2-(2-(3-chlorophenyl)-2-oxoacetamido)-N-((S)-5...)
Affinity DataIC50:  254nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183937((S)-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-but...)
Affinity DataIC50:  425nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183938((S)-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-but...)
Affinity DataIC50:  431nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50228762((S)-2-[3-(3,4-dichloro-benzyl)-ureido]-N-[(S)-4-gu...)
Affinity DataIC50:  480nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50228758((S)-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-but...)
Affinity DataIC50:  502nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183925((S)-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-but...)
Affinity DataIC50:  713nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183934((S)-2-[(R)-2-(2-chloro-phenyl)-2-hydroxy-acetylami...)
Affinity DataIC50:  790nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50228892(4-methyl-pentanoic acid {(S)-1-[(S)-4-guanidino-1-...)
Affinity DataIC50:  850nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183924((S)-2-[(R)-2-(3-fluoro-phenyl)-2-hydroxy-acetylami...)
Affinity DataIC50:  956nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183946((S)-2-{3-[(R)-1-(4-bromo-phenyl)-ethyl]-ureido}-N-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183943((S)-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-but...)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183942((S)-2-((R)-2-amino-2-phenyl-acetylamino)-N-[(S)-4-...)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183933(CHEMBL210731 | naphthalene-1-carboxylic acid [(S)-...)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183935((S)-2-{3-[(R)-1-(4-fluoro-phenyl)-ethyl]-ureido}-N...)
Affinity DataIC50:  2.32E+3nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183926((S)-N-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-but...)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183931(6-fluoro-4H-benzo[1,3]dioxine-8-carboxylic acid [(...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183941((S)-N*4*-(3,4-dichloro-benzyl)-N*1*-[(S)-4-guanidi...)
Affinity DataIC50:  6.22E+3nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183932((S)-2-{3-[(S)-1-(4-bromo-phenyl)-ethyl]-ureido}-N-...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183927(2-(3,4-dichloro-phenyl)-N-[(S)-4-guanidino-1-(thia...)
Affinity DataIC50:  3.79E+4nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183930(CHEMBL207052 | naphthalene-2-sulfonic acid [(S)-4-...)
Affinity DataIC50:  8.60E+4nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183936(CHEMBL380455 | N-[(S)-4-guanidino-1-(thiazole-2-ca...)
Affinity DataIC50:  1.23E+5nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183944(CHEMBL383007 | naphthalene-2-carboxylic acid [(S)-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183928(CHEMBL208645 | naphthalene-1-sulfonic acid [(S)-4-...)
Affinity DataIC50:  2.50E+5nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Daiichi Asubio Medical Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50183945(CHEMBL378011 | N-[(S)-4-guanidino-1-(thiazole-2-ca...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of F11aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed