Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50035916
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007346BDBM50007346(CHEMBL323472 | N-[1-(3-Acetylamino-phenyl)-2-pyrro...)
Affinity DataIC50: 5.5nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007344BDBM50007344(2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2-pyr...)
Affinity DataIC50: 6.90nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007355BDBM50007355(2-(3,4-Dichloro-phenyl)-N-methyl-N-((S)-2-methyl-1...)
Affinity DataIC50: 6.90nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007351BDBM50007351(CHEMBL326899 | N-[2-(Allyl-methyl-amino)-1-phenyl-...)
Affinity DataIC50: 8.20nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007375BDBM50007375(CHEMBL324411 | 2-(3,4-Dichloro-phenyl)-N-[1-(4-hyd...)
Affinity DataIC50: 9.80nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007374BDBM50007374(CHEMBL105942 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 10nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007340BDBM50007340(CHEMBL108344 | 2-(3,4-Dichloro-phenyl)-N-[2-(2,5-d...)
Affinity DataIC50: 11nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007367BDBM50007367(CHEMBL109205 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 11nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007362BDBM50007362(CHEMBL325112 | 2-(3,4-Dichloro-phenyl)-N-[1-(3-hyd...)
Affinity DataIC50: 12nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007377BDBM50007377(CHEMBL320882 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 12nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007368BDBM50007368(CHEMBL324682 | N-Methyl-N-(2-methyl-1-pyrrolidin-1...)
Affinity DataIC50: 14nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007336BDBM50007336(CHEMBL106760 | N-[1-(3-Amino-phenyl)-2-pyrrolidin-...)
Affinity DataIC50: 14nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007383BDBM50007383(CHEMBL321061 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 14nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007372BDBM50007372(CHEMBL323410 | 2-(3,4-Dichloro-phenyl)-N-{1-[(isop...)
Affinity DataIC50: 15nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007341BDBM50007341(CHEMBL106211 | 2-(3,4-Dichloro-phenyl)-N-[1-(2-met...)
Affinity DataIC50: 17nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007378BDBM50007378(CHEMBL107543 | N-Methyl-N-(2-methyl-1-pyrrolidin-1...)
Affinity DataIC50: 21nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007357BDBM50007357(CHEMBL110273 | 2-(3,4-Dichloro-phenyl)-N-[1-(2-hyd...)
Affinity DataIC50: 22nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007380BDBM50007380(CHEMBL108376 | N-[1-(3-Cyano-phenyl)-2-pyrrolidin-...)
Affinity DataIC50: 25nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007360BDBM50007360(CHEMBL106471 | 2-(3,4-Dichloro-phenyl)-N-(2,2-dime...)
Affinity DataIC50: 25nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281663BDBM50281663(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataIC50: 29nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007370BDBM50007370(CHEMBL105923 | 2-(3,4-Dichloro-phenyl)-N-[1-(3-met...)
Affinity DataIC50: 31nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007350BDBM50007350(CHEMBL326698 | 2-(3,4-Dichloro-phenyl)-N-[1-(3,4-d...)
Affinity DataIC50: 33nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007365BDBM50007365(CHEMBL108618 | 2-(4-Chloro-phenyl)-N-methyl-N-(2-m...)
Affinity DataIC50: 37nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007364BDBM50007364(CHEMBL110718 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 39nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007354BDBM50007354(CHEMBL105984 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 39nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007361BDBM50007361(CHEMBL56651 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-(...)
Affinity DataIC50: 53nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007369BDBM50007369(CHEMBL110924 | N-[1-(3-Chloro-phenyl)-2-pyrrolidin...)
Affinity DataIC50: 58nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007376BDBM50007376(CHEMBL105783 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 65nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007349BDBM50007349(CHEMBL320064 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 71nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007352BDBM50007352(CHEMBL108998 | 2-(3,4-Dichloro-phenyl)-N-[1-(4-met...)
Affinity DataIC50: 73nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007353BDBM50007353(CHEMBL110867 | 2-(3,4-Dichloro-phenyl)-N-(1-diethy...)
Affinity DataIC50: 81nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007381BDBM50007381(CHEMBL107780 | N-Methyl-N-(2-methyl-1-pyrrolidin-1...)
Affinity DataIC50: 92nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000296BDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50: 96nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007359BDBM50007359(CHEMBL106510 | 2-(3-Chloro-phenyl)-N-methyl-N-(2-m...)
Affinity DataIC50: 99nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007347BDBM50007347(CHEMBL106955 | 2-(3,4-Difluoro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 101nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007382BDBM50007382(CHEMBL107461 | 2-(3,4-Dichloro-phenyl)-N-(1-dimeth...)
Affinity DataIC50: 105nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007373BDBM50007373(CHEMBL110190 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 124nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007363BDBM50007363(CHEMBL110835 | N-Methyl-N-(2-methyl-1-pyrrolidin-1...)
Affinity DataIC50: 206nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007345BDBM50007345(CHEMBL110599 | 2-(3,4-Dichloro-phenyl)-N-[1-(2,4-d...)
Affinity DataIC50: 248nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007342BDBM50007342(CHEMBL106954 | 2-(4-Cyano-phenyl)-N-methyl-N-(2-me...)
Affinity DataIC50: 277nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007337BDBM50007337(CHEMBL106726 | N-Ethyl-N-(2-methyl-1-pyrrolidin-1-...)
Affinity DataIC50: 322nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007358BDBM50007358(CHEMBL107652 | N-Methyl-N-(2-methyl-1-pyrrolidin-1...)
Affinity DataIC50: 420nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007366BDBM50007366(CHEMBL110834 | N-(2-Methyl-1-pyrrolidin-1-ylmethyl...)
Affinity DataIC50: 485nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007348BDBM50007348(CHEMBL107358 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 625nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007335BDBM50007335(CHEMBL108393 | N-Methyl-N-(2-methyl-1-pyrrolidin-1...)
Affinity DataIC50: 656nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007379BDBM50007379(CHEMBL107702 | 2-(4-Methoxy-phenyl)-N-methyl-N-(2-...)
Affinity DataIC50: 909nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007338BDBM50007338(CHEMBL420115 | 2-(3,4-Dichloro-phenyl)-N-methyl-N-...)
Affinity DataIC50: 1.02E+3nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007339BDBM50007339(CHEMBL109115 | N-(2-Methyl-1-pyrrolidin-1-ylmethyl...)
Affinity DataIC50: 1.44E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007343BDBM50007343(CHEMBL327120 | N-{1-[(Benzyl-methyl-amino)-methyl]...)
Affinity DataIC50: 1.61E+3nMAssay Description:Binding affinity against Opioid receptor kappa 1, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000092BDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataIC50: 2.39E+3nMAssay Description:Binding affinity against opioid receptor kappa, in guinea pig brain membrane, using [3H]bremazocine as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
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