Compile Data Set for Download or QSAR
maximum 50k data
Found 89 Enz. Inhib. hit(s) with all data for entry = 50017667
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185178(1-tert-butyl-3-(3-(5-(4-(piperidin-1-yl)piperidin-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185178(1-tert-butyl-3-(3-(5-(4-(piperidin-1-yl)piperidin-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185181(5-(4-(piperidin-1-yl)piperidin-1-yl)-2-(6-(trifluo...)
Affinity DataIC50:  2nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185181(5-(4-(piperidin-1-yl)piperidin-1-yl)-2-(6-(trifluo...)
Affinity DataIC50:  2nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185173(1-tert-butyl-3-(3-(5-(4-(piperidin-1-yl)piperidin-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185173(1-tert-butyl-3-(3-(5-(4-(piperidin-1-yl)piperidin-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185178(1-tert-butyl-3-(3-(5-(4-(piperidin-1-yl)piperidin-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185177(2-(1H-indazol-3-yl)-N-methyl-N-(1-methylpiperidin-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185169(2-(5-phenoxy-1H-indazol-3-yl)-5-(4-(piperidin-1-yl...)
Affinity DataIC50:  8nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185172(2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185184(2-(6-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185183(CHEMBL380372 | methyl 3-(5-(4-(piperidin-1-yl)pipe...)
Affinity DataIC50:  15nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185169(2-(5-phenoxy-1H-indazol-3-yl)-5-(4-(piperidin-1-yl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185171(CHEMBL379108 | N-(cyclohexylmethyl)-3-(5-(4-(piper...)
Affinity DataIC50:  16nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185177(2-(1H-indazol-3-yl)-N-methyl-N-(1-methylpiperidin-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185171(CHEMBL379108 | N-(cyclohexylmethyl)-3-(5-(4-(piper...)
Affinity DataIC50:  21nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185184(2-(6-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185184(2-(6-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50:  23nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50181305(4-amino-3-(1H-benzo[d]imidazol-2-yl)quinolin-2(1H)...)
Affinity DataIC50:  25nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185172(2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...)
Affinity DataIC50:  28nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185172(2-(6-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...)
Affinity DataIC50:  28nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185169(2-(5-phenoxy-1H-indazol-3-yl)-5-(4-(piperidin-1-yl...)
Affinity DataIC50:  28nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185170(2-(1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin...)
Affinity DataIC50:  28nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185183(CHEMBL380372 | methyl 3-(5-(4-(piperidin-1-yl)pipe...)
Affinity DataIC50:  31nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185174(2-(1H-indazol-3-yl)-5-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50:  44nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185169(2-(5-phenoxy-1H-indazol-3-yl)-5-(4-(piperidin-1-yl...)
Affinity DataIC50:  44nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185171(CHEMBL379108 | N-(cyclohexylmethyl)-3-(5-(4-(piper...)
Affinity DataIC50:  44nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185170(2-(1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin...)
Affinity DataIC50:  48nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185186(2-(1H-indazol-3-yl)-5-(3-(pyrrolidin-1-yl)propoxy)...)
Affinity DataIC50:  48nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185175(2-(1H-indazol-3-yl)-5-morpholino-1H-benzo[d]imidaz...)
Affinity DataIC50:  50nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185181(5-(4-(piperidin-1-yl)piperidin-1-yl)-2-(6-(trifluo...)
Affinity DataIC50:  52nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185181(5-(4-(piperidin-1-yl)piperidin-1-yl)-2-(6-(trifluo...)
Affinity DataIC50:  62nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185183(CHEMBL380372 | methyl 3-(5-(4-(piperidin-1-yl)pipe...)
Affinity DataIC50:  63nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185176(2-(4-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50:  63nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185173(1-tert-butyl-3-(3-(5-(4-(piperidin-1-yl)piperidin-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185183(CHEMBL380372 | methyl 3-(5-(4-(piperidin-1-yl)pipe...)
Affinity DataIC50:  73nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185170(2-(1H-indazol-3-yl)-5-(4-(piperidin-1-yl)piperidin...)
Affinity DataIC50:  78nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185178(1-tert-butyl-3-(3-(5-(4-(piperidin-1-yl)piperidin-...)
Affinity DataIC50:  81nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185174(2-(1H-indazol-3-yl)-5-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50:  82nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185182(2-(5-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50:  83nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185188(5-(1H-imidazol-1-yl)-2-(1H-indazol-3-yl)-1H-benzo[...)
Affinity DataIC50:  83nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185176(2-(4-(benzyloxy)-1H-indazol-3-yl)-5-(4-(piperidin-...)
Affinity DataIC50:  94nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185188(5-(1H-imidazol-1-yl)-2-(1H-indazol-3-yl)-1H-benzo[...)
Affinity DataIC50:  96nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185186(2-(1H-indazol-3-yl)-5-(3-(pyrrolidin-1-yl)propoxy)...)
Affinity DataIC50:  98nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185175(2-(1H-indazol-3-yl)-5-morpholino-1H-benzo[d]imidaz...)
Affinity DataIC50:  100nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Chiron

Curated by ChEMBL
LigandPNGBDBM50185174(2-(1H-indazol-3-yl)-5-(4-methylpiperazin-1-yl)-1H-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chiron

Curated by ChEMBL
LigandPNGBDBM50185179(2-(7-fluoro-1H-indazol-3-yl)-5-(4-(piperidin-1-yl)...)
Affinity DataIC50:  150nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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