Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50017815
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187007(5-chloro-3-(3,4-dioxo-2-(phenylamino)cyclobut-1-en...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187004(3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50:  2nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187002(4-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187003(3-(3,4-dioxo-2-(pentan-3-ylamino)cyclobut-1-enylam...)
Affinity DataIC50:  5nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50186997(3-(2-(cyclopentylamino)-3,4-dioxocyclobut-1-enylam...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187016(2-hydroxy-3-(2-(isopropylamino)-3,4-dioxocyclobut-...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187015(3-(2-(cyclohexylamino)-3,4-dioxocyclobut-1-enylami...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187014(3-(2-(tert-butylamino)-3,4-dioxocyclobut-1-enylami...)
Affinity DataIC50:  14nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187010(3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50:  22nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187011(3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50:  34nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187001(3-(2-hydroxy-4-nitrophenylamino)-4-(phenylamino)cy...)
Affinity DataIC50:  36nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50186999(3-(2-(furan-2-ylmethylamino)-3,4-dioxocyclobut-1-e...)
Affinity DataIC50:  41nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187017(CHEMBL380052 | methyl 3-(3,4-dioxo-2-(phenylamino)...)
Affinity DataIC50:  53nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50186998(3-(2-hydroxy-5-nitrophenylamino)-4-(phenylamino)cy...)
Affinity DataIC50:  56nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187019(3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50:  65nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187009(3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50:  74nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187012(CHEMBL436940 | N-benzyl-3-(3,4-dioxo-2-(phenylamin...)
Affinity DataIC50:  139nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187020(3-(3,4-dioxo-2-(tetrahydro-2H-pyran-4-ylamino)cycl...)
Affinity DataIC50:  171nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187006(3-(2-hydroxyphenylamino)-4-(phenylamino)cyclobut-3...)
Affinity DataIC50:  476nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187008((R)-3-(2-(2,3-dihydro-1H-inden-1-ylamino)-3,4-diox...)
Affinity DataIC50:  548nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187021(3-(3,4-dioxo-2-(phenethylamino)cyclobut-1-enylamin...)
Affinity DataIC50:  926nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187000(3-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187013(4-(3,4-dioxo-2-(phenylamino)cyclobut-1-enylamino)-...)
Affinity DataIC50:  3.10E+3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187018(2-hydroxy-N,N-dimethyl-3-(2-(methyl(phenyl)amino)-...)
Affinity DataIC50:  7.20E+3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187005(3-(4-nitrophenylamino)-4-(phenylamino)cyclobut-3-e...)
Affinity DataIC50:  8.60E+3nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50187022(3-((2-hydroxyphenyl)(methyl)amino)-4-(phenylamino)...)
Affinity DataIC50:  2.86E+4nMAssay Description:Displacement of [125I]IL8 from human CXCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed