Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50000589
TargetD(1A) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity determined in radioreceptor binding assay by using [3H]SCH-23390 radioligand against dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  0.570nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 2 receptor using ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  0.570nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 2 receptor using ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  0.660nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  1nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 2 receptor using ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  1nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 2 receptor using ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  2nMAssay Description:The compound was tested for binding affinity against dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  2nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  3.10nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D1 using SCH-23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  4.30nMAssay Description:The compound was tested for binding affinity against muscarinic acetylcholine receptor using QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  6.5nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D2 using raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  7.20nMAssay Description:The compound was tested for binding affinity against Muscarinic acetylcholine receptor using QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  12nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB-4101 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  12nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB-4101 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  36nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB-4101 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  36nMAssay Description:The compound was tested for binding affinity against Alpha-1 adrenergic receptor using WB-4101 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  94nMAssay Description:The compound was tested for binding affinity against muscarinic acetylcholine receptor using QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  94nMAssay Description:The compound was tested for binding affinity against muscarinic acetylcholine receptor using QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  550nMAssay Description:The compound was tested for binding affinity against Sigma opioid receptor using DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007551(Enantiomer 1'3'-chlorospiro[2-cyclohexene-1,5'-(10...)
Affinity DataKi:  550nMAssay Description:The compound was tested for binding affinity against sigma receptor using DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  800nMAssay Description:The compound was tested for binding affinity against Sigma opioid receptor using DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50007550(3'-chlorospiro[2-cyclohexene-1,5'-(10',11'-dihydro...)
Affinity DataKi:  800nMAssay Description:The compound was tested for binding affinity against Sigma opioid receptor using DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed