Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 2116
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17060BDBM17060(CHEMBL319556 | 1-(2,6-dichlorophenyl)-5-(2,4-diflu...)
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17061BDBM17061(1-(2,6-dichlorophenyl)-5-(2,4-difluorophenyl)-7-[1...)
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17081BDBM17081(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-({8-me...)
Affinity DataIC50: 0.5nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17074BDBM17074(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-{4-[2-...)
Affinity DataIC50: 0.5nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17082BDBM17082(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-{[1-(p...)
Affinity DataIC50: 0.600nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17083BDBM17083(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-[(2,2,...)
Affinity DataIC50: 0.700nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17068BDBM17068(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-[(2,2-...)
Affinity DataIC50: 0.800nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17056BDBM17056(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-methox...)
Affinity DataIC50: 1nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17075BDBM17075(5-(2,4-dichlorophenyl)-1-(2,6-dichlorophenyl)-7-{4...)
Affinity DataIC50: 1nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17067BDBM17067(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(propa...)
Affinity DataIC50: 1.10nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17080BDBM17080(7-{1-azabicyclo[2.2.2]octan-3-ylamino}-5-(2-chloro...)
Affinity DataIC50: 1.20nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17069BDBM17069(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-{1H,4H...)
Affinity DataIC50: 1.90nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17065BDBM17065(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(methy...)
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17071BDBM17071(5-(2,4-dichlorophenyl)-1-(2,6-dichlorophenyl)-7-[(...)
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17058BDBM17058(CHEMBL94556 | methyl 5-(2-chlorophenyl)-1-(2,6-dic...)
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17059BDBM17059(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-hydrox...)
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17078BDBM17078(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(morph...)
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17079BDBM17079(5-(2,4-dichlorophenyl)-1-(2,6-dichlorophenyl)-7-[(...)
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17066BDBM17066(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(dimet...)
Affinity DataIC50: 3nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17070BDBM17070(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-hydrox...)
Affinity DataIC50: 4nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17077BDBM17077(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(morph...)
Affinity DataIC50: 4nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17073BDBM17073(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-[2-(di...)
Affinity DataIC50: 4.20nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17063BDBM17063(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-methan...)
Affinity DataIC50: 4.20nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17064BDBM17064(7-amino-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-...)
Affinity DataIC50: 5.30nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17072BDBM17072(5-(2,4-dichlorophenyl)-1-(2,6-dichlorophenyl)-7-{[...)
Affinity DataIC50: 5.60nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17057BDBM17057(7-amino-5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-...)
Affinity DataIC50: 6nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17062BDBM17062(5-(2-chlorophenyl)-1-(2,6-dichlorophenyl)-7-(methy...)
Affinity DataIC50: 10nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandChemical structure of BindingDB Monomer ID 17076BDBM17076(5-(2,4-dichlorophenyl)-1-(2,6-dichlorophenyl)-7-[4...)
Affinity DataIC50: 20nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMed