Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50000601
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 3.90nMAssay Description:Compound was tested for the binding affinity against sigma receptor by using [3H]-+3PPP as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 100nMAssay Description:Compound was tested for the binding affinity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 110nMAssay Description:Compound was tested for the binding affinity against Alpha-1 adrenergic receptor by using [3H]prazosin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131677BDBM50131677(CHEMBL106970)
Affinity DataIC50: 130nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 135nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131671BDBM50131671(CHEMBL104625)
Affinity DataIC50: 220nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 238nMAssay Description:Compound was tested for the binding affinity against 5-hydroxytryptamine 1A receptor by using [3H]DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50007676BDBM50007676(CHEMBL553596 | CHEMBL18222 | 4-Benzyl-1-phenethyl-...)
Affinity DataIC50: 347nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131674BDBM50131674(CHEMBL321349)
Affinity DataIC50: 400nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131542BDBM50131542(CHEMBL102242)
Affinity DataIC50: 573nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Bovine)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 610nMAssay Description:Compound was tested for the binding affinity against 5-hydroxytryptamine 2 receptor by using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50007677BDBM50007677(4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 843nMAssay Description:Compound was tested for the binding affinity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the binding affinity against opioid receptor mu by using [3H]naloxone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the binding affinity against muscarinic acetylcholine receptor
by using [3H]QNB as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the binding affinity against dopamine receptor D1 by using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the binding affinity against histamine H1 receptor by using [3H]mepyramine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007674BDBM50007674((+)-erythro 4-[2-(4-Benzyl-piperidin-1-yl)-1-hydro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the binding affinity against dopamine receptor D2 by using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131540BDBM50131540(CHEMBL106969)
Affinity DataIC50: 2.13E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50007677BDBM50007677(4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50007677BDBM50007677(4-[(1S,2S)-2-(4-Benzyl-piperidin-1-yl)-1-hydroxy-p...)
Affinity DataIC50: 2.31E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131673BDBM50131673(CHEMBL323338)
Affinity DataIC50: 2.57E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131662BDBM50131662(CHEMBL104363)
Affinity DataIC50: 2.87E+3nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131676BDBM50131676(CHEMBL262807)
Affinity DataIC50: 4.63E+3nMAssay Description:Compound was tested for the binding affinity against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131672BDBM50131672(CHEMBL102212)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131543BDBM50131543(CHEMBL318347)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131675BDBM50131675(CHEMBL322633)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50131541BDBM50131541(CHEMBL104318)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed