Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50018037
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190268BDBM50190268(4'-methylsulfanyl-biphenyl-4-carboxylic acid methy...)
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity against human MCHR1 expressed in CHO cells assessed by inhibition of MCH-stimulated G protein-GTP-gamma-[35S] bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190268BDBM50190268(4'-methylsulfanyl-biphenyl-4-carboxylic acid methy...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190279BDBM50190279(4'-chloro-biphenyl-4-carboxylic acid methyl-{(S)-1...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190280BDBM50190280(4'-trifluoromethoxy-biphenyl-4-carboxylic acid met...)
Affinity DataKi:  7nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190267BDBM50190267(4'-methoxy-biphenyl-4-carboxylic acid methyl-{(S)-...)
Affinity DataKi:  8nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190296BDBM50190296(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  10nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190263BDBM50190263(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190293BDBM50190293(4'-trifluoromethyl-biphenyl-4-carboxylic acid {(S)...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190281BDBM50190281(4'-trifluoromethyl-biphenyl-4-carboxylic acid {(S)...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190261BDBM50190261(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  13nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190290BDBM50190290(4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190303BDBM50190303(4'-trifluoromethyl-biphenyl-4-carboxylic acid [(S)...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190274BDBM50190274(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190291BDBM50190291(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190272BDBM50190272(4'-fluoro-biphenyl-4-carboxylic acid methyl-{(S)-1...)
Affinity DataKi:  19nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190297BDBM50190297(4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)...)
Affinity DataKi:  19nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190302BDBM50190302(4'-trifluoromethyl-biphenyl-4-carboxylic acid {(S)...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190265BDBM50190265(4'-trifluoromethyl-biphenyl-4-carboxylic acid {(S)...)
Affinity DataKi:  22nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190266BDBM50190266(4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)...)
Affinity DataKi:  22nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190298BDBM50190298(4'-trifluoromethyl-biphenyl-4-carboxylic acid {(S)...)
Affinity DataKi:  24nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190278BDBM50190278(4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)...)
Affinity DataKi:  26nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190277BDBM50190277(4'-trifluoromethyl-biphenyl-4-carboxylic acid [(S)...)
Affinity DataKi:  27nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190289BDBM50190289(4'-trifluoromethyl-biphenyl-4-carboxylic acid {(S)...)
Affinity DataKi:  28nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190270BDBM50190270(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  29nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190282BDBM50190282(4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190301BDBM50190301(4'-trifluoromethyl-biphenyl-4-carboxylic acid [(S)...)
Affinity DataKi:  34nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190264BDBM50190264(4'-trifluoromethyl-biphenyl-4-carboxylic acid {(S)...)
Affinity DataKi:  38nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190271BDBM50190271(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  40nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190294BDBM50190294(4'-trifluoromethyl-biphenyl-4-carboxylic acid {(S)...)
Affinity DataKi:  42nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190283BDBM50190283(4-(6-methoxy-pyridin-3-yl)-N-methyl-N-{(S)-1-[(S)-...)
Affinity DataKi:  44nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190262BDBM50190262(4'-trifluoromethyl-biphenyl-4-carboxylic acid [(S)...)
Affinity DataKi:  48nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190273BDBM50190273(4'-cyano-biphenyl-4-carboxylic acid methyl-{(S)-1-...)
Affinity DataKi:  49nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190287BDBM50190287(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  51nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190260BDBM50190260(4'-trifluoromethyl-biphenyl-4-carboxylic acid [(S)...)
Affinity DataKi:  51nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190295BDBM50190295(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  53nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190258BDBM50190258(4'-trifluoromethyl-biphenyl-4-carboxylic acid {(S)...)
Affinity DataKi:  54nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190261BDBM50190261(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataIC50: 55nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190275BDBM50190275(4'-(methyl-{(S)-1-[(S)-3-(3-phenyl-propylamino)-py...)
Affinity DataKi:  73nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190292BDBM50190292(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  110nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190300BDBM50190300((S)-3-[methyl-(4'-trifluoromethyl-biphenyl-4-carbo...)
Affinity DataIC50: 170nMAssay Description:Inhibition of HERG potassium channel expressed in HEK cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190288BDBM50190288(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataKi:  180nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190286BDBM50190286(N-methyl-N-{(S)-1-[(S)-3-(3-phenyl-propylamino)-py...)
Affinity DataKi:  400nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190284BDBM50190284(biphenyl-4,4'-dicarboxylic acid 4-amide 4'-(methyl...)
Affinity DataKi:  630nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190276BDBM50190276(N-methyl-N-{(S)-1-[(S)-3-(3-phenyl-propylamino)-py...)
Affinity DataKi:  640nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190299BDBM50190299(4-(5-methoxy-pyridin-3-yl)-N-methyl-N-{(S)-1-[(S)-...)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190296BDBM50190296(4'-trifluoromethyl-biphenyl-4-carboxylic acid meth...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190290BDBM50190290(4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of HERG potassium channel expressed in HEK cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190290BDBM50190290(4'-trifluoromethyl-biphenyl-4-carboxylic acid ((S)...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190269BDBM50190269(4'-acetylamino-biphenyl-4-carboxylic acid methyl-{...)
Affinity DataKi:  4.00E+3nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50190259BDBM50190259(N-methyl-N-{(S)-1-[(S)-3-(3-phenyl-propylamino)-py...)
Affinity DataKi:  4.80E+3nMAssay Description:Displacement of [125I-Tyr13]MCH from human MCHR1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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